About the Authors

Josef D. Järhult

josef.jarhult@medsci.uu.se

Affiliation Section of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden

Shaman Muradrasoli

Contributed equally to this work with: Shaman Muradrasoli, John Wahlgren

Affiliation Section of Bacteriology and Food Safety, Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden

John Wahlgren

Contributed equally to this work with: Shaman Muradrasoli, John Wahlgren

Affiliation Swedish Institute for Infectious Disease Control and Karolinska Institute, Microbiology and Tumor Biology Center, Stockholm, Sweden

Hanna Söderström

Affiliation Department of Chemistry, Umeå University, Umeå, Sweden

Goran Orozovic

Affiliation Section for Zoonotic Ecology and Epidemiology, School of Natural Sciences, Linnaeus University, Kalmar, Sweden

Gunnar Gunnarsson

Affiliations Section for Zoonotic Ecology and Epidemiology, School of Natural Sciences, Linnaeus University, Kalmar, Sweden, Aquatic Biology and Chemistry Group, Kristianstad University, Kristianstad, Sweden

Caroline Bröjer

Affiliations National Veterinary Institute, Uppsala, Sweden, Section of Pathology, Pharmacology and Toxicology, Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden

Neus Latorre-Margalef

Affiliation Section for Zoonotic Ecology and Epidemiology, School of Natural Sciences, Linnaeus University, Kalmar, Sweden

Jerker Fick

Affiliation Department of Chemistry, Umeå University, Umeå, Sweden

Roman Grabic

Affiliations Department of Chemistry, Umeå University, Umeå, Sweden, Research Institute of Fish Culture and Hydrobiology, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic

Johan Lennerstrand

Affiliation Section of Clinical Virology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden

Jonas Waldenström

Affiliation Section for Zoonotic Ecology and Epidemiology, School of Natural Sciences, Linnaeus University, Kalmar, Sweden

Åke Lundkvist

Affiliation Swedish Institute for Infectious Disease Control and Karolinska Institute, Microbiology and Tumor Biology Center, Stockholm, Sweden

Björn Olsen

Affiliations Section of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, Section for Zoonotic Ecology and Epidemiology, School of Natural Sciences, Linnaeus University, Kalmar, Sweden

Competing Interests

F. Hoffman - La Roche Ltd. (www.roche.com) provided deuterium-labeled OC for the experiment. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JDJ SM JW HS GG NLM JF JW ÅL BO. Performed the experiments: JDJ SM JW HS GG CB NLM JF RG. Analyzed the data: JDJ SM HS GO JL BO. Wrote the paper: JDJ SM JW HS NLM BO. Drafted and/or critically revised the article: GO GG CB JF RG JL JW ÅL.