About the Authors
- Yasuaki Sanada
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Affiliations Departments of Complementary and Alternative Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan, Department of Hospital Pharmacy Education, Graduate School of Pharmaceutical Science, Osaka University, Osaka, Japan
- Tsunekazu Mizushima
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Affiliation Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
- Yasuyuki Kai
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Affiliation Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
- Junichi Nishimura
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Affiliation Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
- Hiroshi Hagiya
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Affiliation Minase Research Institute, Ono Pharmaceutical Co., Ltd, Osaka, Japan
- Haruto Kurata
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Affiliation Minase Research Institute, Ono Pharmaceutical Co., Ltd, Osaka, Japan
- Hirotaka Mizuno
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Affiliation Tsukuba Research Institute, Ono Pharmaceutical Co., Ltd, Ibaraki, Japan
- Etsuko Uejima
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Affiliation Department of Hospital Pharmacy Education, Graduate School of Pharmaceutical Science, Osaka University, Osaka, Japan
- Toshinori Ito
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* E-mail: juki@cam.med.osaka-u.ac.jp
Affiliation Departments of Complementary and Alternative Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
Competing Interests
YS, TM, YK, JN, EU and TI have declared that no competing interests exist. HH, HK, and HM are employers of Ono Pharmaceutical Co., Ltd. This company did not provide direct financial support, it can be considered to be as an indirect funder for this study. This company provided us a base powder of W-061 free of charge and some in vitro pharmacological data. There are no patents, products in development or marketed products to declare. The authors confirm that this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: TM YK JN TI. Performed the experiments: YS JN HH HK HM. Analyzed the data: YS TM YK JN EU TI. Contributed reagents/materials/analysis tools: HH HK HM. Wrote the paper: YS TI.