About the Authors

Anette P. Gjesing

anette.gjesing@sund.ku.dk

Affiliations Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

Marie A. Vestmar

Affiliations Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark

Torben Jørgensen

Affiliations Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark

Martin Heni

Affiliation Department of Internal Medicine, Eberhard Karls University Tübingen, Tübingen, Germany

Jens J. Holst

Affiliation Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark

Daniel R. Witte

Affiliation Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark

Torben Hansen

Affiliations Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark

Oluf Pedersen

Affiliations Steno Diabetes Center and Hagedorn Research Institute, Copenhagen, Denmark, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Science, Aarhus University, Aarhus, Denmark

Competing Interests

The authors have read the journal's policy and have the following conflicts: APG, MAV, TJ, TH and JJH have nothing to declare. DRW is employed by Steno Diabetes Center, a teaching and research hospital owned by Novo Nordisk and has personal Novo Nordisk shares. OP is employed by Hagedorn Research Institute, which is a basic research facility of Novo Nordisk and both have employee shares in Novo Nordisk. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TH OP APG. Performed the experiments: APG MAV MH. Analyzed the data: APG MAV MH. Contributed reagents/materials/analysis tools: TJ DRW JJH MH. Wrote the paper: APG MAV TH OP.