About the Authors

Zhongjie Liang

Contributed equally to this work with: Zhongjie Liang, Lianchun Li, Yuanyuan Wang

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Lianchun Li

Contributed equally to this work with: Zhongjie Liang, Lianchun Li, Yuanyuan Wang

Affiliations Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Yuanyuan Wang

Contributed equally to this work with: Zhongjie Liang, Lianchun Li, Yuanyuan Wang

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Limin Chen

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Xiangqian Kong

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Yao Hong

Affiliation State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Lefu Lan

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Mingyue Zheng

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Cai Guang-Yang

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Hong Liu

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Xu Shen

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Cheng Luo

cluo@mail.shcnc.ac.cn (CL); hljiang@mail.shcnc.ac.cn (HJ); kli@epigenetic.us (KL)

Affiliations Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, Center for Systems Biology, Soochow University, Jiangsu, China

Keqin Kathy Li

cluo@mail.shcnc.ac.cn (CL); hljiang@mail.shcnc.ac.cn (HJ); kli@epigenetic.us (KL)

Affiliation State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Kaixian Chen

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Hualiang Jiang

cluo@mail.shcnc.ac.cn (CL); hljiang@mail.shcnc.ac.cn (HJ); kli@epigenetic.us (KL)

Affiliations Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, School of Pharmacy, East China University of Science and Technology, Shanghai, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZL L. Lianchunli YW XS CG-Y HL KL HJ CL. Performed the experiments: ZL L. Lianchunli YW KL HJ CL. Analyzed the data: ZL L. Lianchunli YW LC XK YH L. Lefulan MZ CG-Y HL XS CL KL KC HJ. Contributed reagents/materials/analysis tools: ZL L. Lianchunli LC XK YW YH CL KL HJ. Wrote the paper: ZL L. Lianchunli YW CL KL HJ.