About the Authors

Rui-Min Zhou

Affiliations State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China, Henan Provincial Center for Disease Control and Prevention, Zhengzhou, Henan Province, People's Republic of China

Yuan-Yuan Jing

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Yan Guo

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Chen Gao

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Bao-Yun Zhang

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Cao Chen

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Qi Shi

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Chan Tian

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Zhao-Yun Wang

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Han-Shi Gong

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Jun Han

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Bian-Li Xu

Affiliation Henan Provincial Center for Disease Control and Prevention, Zhengzhou, Henan Province, People's Republic of China

Xiao-Ping Dong

dongxp238@sina.com

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the experiments: R-MZ. Analyzed the data: R-MZ. Wrote the paper: R-MZ B-LX X-PD. Designed the study: X-PD. Helped to construct the plasmids and supply the some experimental materials: Y-YJ YG CG CC QS Z-YW H-SG. Involved in Western blots for PrP: B-YZ QS CT. Helped to perform ThT and EM assays: JH.