About the Authors

Steve C.-Y. Chen

Affiliation Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Patrick Stern

Affiliation Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Zhuyan Guo

Affiliation Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Jianzhu Chen

jchen@mit.edu

Affiliation Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Competing Interests

The authors received funding from Cobb-Vantress Inc. to support this work. The authors have declared that no competing interests exist and will adhere to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SC PS JC. Performed the experiments: SC ZG. Analyzed the data: SC PS ZG JC. Contributed reagents/materials/analysis tools: SC PS ZG JC. Wrote the paper: SC PS JC.