About the Authors

Léon J. A. Spijkers

Affiliation Department of Pharmacology and Pharmacotherapy, Academic Medical Center, Amsterdam, The Netherlands

Rob F. P. van den Akker

Affiliation Department of Pharmacology and Pharmacotherapy, Academic Medical Center, Amsterdam, The Netherlands

Ben J. A. Janssen

Affiliation Department of Pharmacology and Toxicology, Maastricht University, Maastricht, The Netherlands

Jacques J. Debets

Affiliation Department of Pharmacology and Toxicology, Maastricht University, Maastricht, The Netherlands

Jo G. R. De Mey

Affiliation Department of Pharmacology and Toxicology, Maastricht University, Maastricht, The Netherlands

Erik S. G. Stroes

Affiliation Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

Bert-Jan H. van den Born

Affiliation Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

Dayanjan S. Wijesinghe

Affiliation Department of Biochemistry, Virginia Commonwealth University, Richmond, Virginia, United States of America

Charles E. Chalfant

Affiliation Department of Biochemistry, Virginia Commonwealth University, Richmond, Virginia, United States of America

Luke MacAleese

Affiliation FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands

Gert B. Eijkel

Affiliation FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands

Ron M. A. Heeren

Affiliation FOM Institute for Atomic and Molecular Physics, Amsterdam, The Netherlands

Astrid E. Alewijnse

Affiliation Department of Pharmacology and Pharmacotherapy, Academic Medical Center, Amsterdam, The Netherlands

Stephan L. M. Peters

s.l.peters@amc.uva.nl

Affiliation Department of Pharmacology and Pharmacotherapy, Academic Medical Center, Amsterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LS BJ JDM ES BJvdB CC RH AA SP. Performed the experiments: LS RvdA JD DW LM. Analyzed the data: LS BJ BJvdB CE GE AA SP. Contributed reagents/materials/analysis tools: CC RH ES BJvdB. Wrote the paper: LS JDM AA SP. Designed the software used in analysis: GE.