About the Authors
- Martin F. Strand
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* E-mail: martin.frank.strand@rr-research.no (MFS); stefan.krauss@rr-research.no (SK)
Affiliation Unit for Cell Signalling, Institute for Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
- Steven R. Wilson
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Affiliation Department of Chemistry, University of Oslo, Oslo, Norway
- Jennifer L. Dembinski
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Affiliation Unit for Cell Signalling, Institute for Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
- Daniel D. Holsworth
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Affiliation ChemDiv Inc., San Diego, California, United States of America
- Alexander Khvat
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Affiliation ChemDiv Inc., San Diego, California, United States of America
- Ilya Okun
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Affiliation ChemDiv Inc., San Diego, California, United States of America
- Dirk Petersen
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Affiliation Department of Chemistry, University of Oslo, Oslo, Norway
- Stefan Krauss
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* E-mail: martin.frank.strand@rr-research.no (MFS); stefan.krauss@rr-research.no (SK)
Affiliation Unit for Cell Signalling, Institute for Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Competing Interests
The chemotype detailed in this study is part of a patent filed by Drs. Alex Khvat, Ilya Okun and others titled: HETEROCYCLIC INHIBITORS OF AN Hh-SIGNAL CASCADE, MEDICINAL COMPOSITIONS BASED THEREON AND METHODS FOR TREATING DISEASES CAUSED BY THE ABERRANT ACTIVITY OF AN Hh-SIGNAL SYSTEM (PCT/IB2008/055258; WO 2009/077956 A2 and WO 2009/077956 A3). There are currently no products arising from the work under development based on the chemotype detailed in this study. None of the authors, aside from Drs. Alex Khvat, Ilya Okun and Dan Holsworth who are employed by ChemDiv Inc, have any financial relationships that could be perceived as relevant. The authors declare no other competing interests. The competing interest detailed here does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MFS SRW JLD DDH AK IO DP SK. Performed the experiments: MFS SRW JLD AK IO DP. Analyzed the data: MFS SRW JLD DDH AK IO DP SK. Contributed reagents/materials/analysis tools: MFS SRW JLD DDH AK IO DP. Wrote the paper: MFS SRW JLD DDH AK IO DP SK.