Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial Cells

Satu Marja Myllymäki; Terhi Piritta Teräväinen; Aki Manninen

doi:10.1371/journal.pone.0019453

Loading metrics

Open Access

Peer-reviewed

Research Article

Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial Cells

Satu Marja Myllymäki,

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
⨯
Terhi Piritta Teräväinen,

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
⨯
Aki Manninen

* E-mail: aki.manninen@oulu.fi

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
⨯

Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial Cells

Satu Marja Myllymäki,
Terhi Piritta Teräväinen,
Aki Manninen

Published: May 6, 2011
https://doi.org/10.1371/journal.pone.0019453

About the Authors

Satu Marja Myllymäki

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland

Terhi Piritta Teräväinen

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland

Aki Manninen

* E-mail: aki.manninen@oulu.fi

Affiliation Biocenter Oulu, Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMM TPT AM. Performed the experiments: SMM TPT AM. Analyzed the data: SMM TPT AM. Contributed reagents/materials/analysis tools: SMM TPT AM. Wrote the paper: AM SMM.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Collagens
Is the Subject Area "Collagens" applicable to this article?

Thanks for your feedback.
Integrins
Is the Subject Area "Integrins" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Actins
Is the Subject Area "Actins" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Cell polarity
Is the Subject Area "Cell polarity" applicable to this article?

Thanks for your feedback.
DAPI staining
Is the Subject Area "DAPI staining" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.