Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence

Catherine Johnson; Tomas Drgon; Donna Walther; George R. Uhl

doi:10.1371/journal.pone.0019210

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Peer-reviewed

Research Article

Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence

Catherine Johnson,

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America
⨯
Tomas Drgon,

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America
⨯
Donna Walther,

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America
⨯
George R. Uhl

* E-mail: guhl@intra.nida.nih.gov

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America
⨯

Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence

Catherine Johnson,
Tomas Drgon,
Donna Walther,
George R. Uhl

Published: July 27, 2011
https://doi.org/10.1371/journal.pone.0019210

About the Authors

Catherine Johnson

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America

Tomas Drgon

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America

Donna Walther

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America

George R. Uhl

* E-mail: guhl@intra.nida.nih.gov

Affiliation Molecular Neurobiology Branch, National Institutes of Health, Intramural Research Program, National Institutes on Drug Abuse, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GRU TD CJ. Performed the experiments: CJ DW TD GRU. Analyzed the data: CJ GRU TD. Contributed reagents/materials/analysis tools: CJ GRU TD. Wrote the paper: GRU TD.

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Single nucleotide polymorphisms
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Drug dependence
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African American people
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Genomics
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Monte Carlo method
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Alcoholism
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Genome-wide association studies
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Genotyping
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