About the Authors

Bai Xue

Affiliation Department of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America

Siddharth Sukumaran

Affiliation Department of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America

Jing Nie

Affiliation Department of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America

William J. Jusko

Affiliations Department of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America, New York State Center of Excellence in Bioinformatics and Life Sciences, Buffalo, New York, United States of America

Debra C. DuBois

Affiliations Department of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America, Department of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America

Richard R. Almon

almon@buffalo.edu

Affiliations Department of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America, Department of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America, New York State Center of Excellence in Bioinformatics and Life Sciences, Buffalo, New York, United States of America

Competing Interests

The UB-Pfizer Strategic Alliance provided money for a variety of purposes to the School of Pharmacy. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DCD RRA WJJ BX JN. Performed the experiments: DCD BX JN SS. Analyzed the data: DCD RRA BX JN SS. Contributed reagents/materials/analysis tools: RRA DCD WJJ. Wrote the paper: BX RRA SS DCD.