About the Authors

Jose A. Morales-Garcia

Affiliation Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas CSIC-UAM, Arturo Duperier, 4 and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain

Miriam Redondo

Affiliation Instituto de Química Médica, CSIC, Juan de la Cierva, Madrid, Spain

Sandra Alonso-Gil

Affiliation Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas CSIC-UAM, Arturo Duperier, 4 and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain

Carmen Gil

Affiliation Instituto de Química Médica, CSIC, Juan de la Cierva, Madrid, Spain

Concepción Perez

Affiliation Instituto de Química Médica, CSIC, Juan de la Cierva, Madrid, Spain

Ana Martinez

Affiliation Instituto de Química Médica, CSIC, Juan de la Cierva, Madrid, Spain

Angel Santos

Affiliation Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

Ana Perez-Castillo

aperez@iib.uam.es

Affiliation Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas CSIC-UAM, Arturo Duperier, 4 and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain

Competing Interests

The authors state that Araclon Biotech has been a commercial funder, together with the MICINN, for this work, but they have not participated in the experimental design on the manuscript and none of the authors is an employee of the company. This funding does not alter the authors' adherence to the PloS ONE policies on sharing data and materials. Some of the results here presented are protected by patent application P200930189 (owner CSIC). A license transfer agreement has been recently reached with ARACLON.

Author Contributions

Conceived and designed the experiments: JAM-G AM AS AP-C. Performed the experiments: JAM-G SA-G CP. Analyzed the data: JAM-G AM AS AP-C. Contributed reagents/materials/analysis tools: MR CG. Wrote the manuscript: JAM-G AS AM AP-C.