About the Authors

Sami Kilpinen

sami.k.kilpinen@helsinki.fi

Affiliation Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Kalle Ojala

Affiliation Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Olli Kallioniemi

Affiliation Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Competing Interests

SK and OK are shareholders in MediSapiens Ltd. SK is inventor in patent application PCT/FI2009/050264. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SK KO. Performed the experiments: SK. Analyzed the data: SK. Contributed reagents/materials/analysis tools: SK KO. Wrote the paper: SK KO OK. Contributed to the concept of the study: SK. Invented and implemented primary methodology: SK. Contributed to the mathematics and the methodology: KO. Participated in the manuscript writing: KO OK. Edited the manuscript: OK. Supervised the entire project: OK.