Ultraviolet Irradiation Induces the Accumulation of Chondroitin Sulfate, but Not Other Glycosaminoglycans, in Human Skin

Benjamin Boegel Werth; Muhammad Bashir; Laura Chang; Victoria P. Werth

doi:10.1371/journal.pone.0014830

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Peer-reviewed

Research Article

Ultraviolet Irradiation Induces the Accumulation of Chondroitin Sulfate, but Not Other Glycosaminoglycans, in Human Skin

Benjamin Boegel Werth,

Affiliations Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Muhammad Bashir,

Affiliations Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Laura Chang,

Affiliations Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Victoria P. Werth

* E-mail: werth@mail.med.upenn.edu

Affiliations Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Ultraviolet Irradiation Induces the Accumulation of Chondroitin Sulfate, but Not Other Glycosaminoglycans, in Human Skin

Benjamin Boegel Werth,
Muhammad Bashir,
Laura Chang,
Victoria P. Werth

Published: August 4, 2011
https://doi.org/10.1371/journal.pone.0014830

About the Authors

Benjamin Boegel Werth

Affiliations Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Muhammad Bashir

Laura Chang

Victoria P. Werth

* E-mail: werth@mail.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BBW VPW. Performed the experiments: BBW MB LC. Analyzed the data: BBW. Contributed reagents/materials/analysis tools: VPW. Wrote the paper: BBW.

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Ultraviolet B
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Skin
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Dermis
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Fibroblasts
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Immunohistochemistry techniques
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Ultraviolet radiation
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Epidermis
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Sulfates
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