Activation of FGF Signaling Mediates Proliferative and Osteogenic Differences between Neural Crest Derived Frontal and Mesoderm Parietal Derived Bone

Shuli Li; Natalina Quarto; Michael T. Longaker

doi:10.1371/journal.pone.0014033

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Open Access

Peer-reviewed

Research Article

Activation of FGF Signaling Mediates Proliferative and Osteogenic Differences between Neural Crest Derived Frontal and Mesoderm Parietal Derived Bone

Shuli Li,

Affiliation Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America
⨯
Natalina Quarto,

Affiliations Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America, Department of Structural and Functional Biology, University of Naples Federico II, Complesso M. S. Angelo, Napoli, Italy
⨯
Michael T. Longaker

* E-mail: Longaker@stanford.edu

Affiliation Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America
⨯

Activation of FGF Signaling Mediates Proliferative and Osteogenic Differences between Neural Crest Derived Frontal and Mesoderm Parietal Derived Bone

Shuli Li,
Natalina Quarto,
Michael T. Longaker

Published: November 18, 2010
https://doi.org/10.1371/journal.pone.0014033

About the Authors

Shuli Li

Affiliation Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America

Natalina Quarto

Affiliations Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America, Department of Structural and Functional Biology, University of Naples Federico II, Complesso M. S. Angelo, Napoli, Italy

Michael T. Longaker

* E-mail: Longaker@stanford.edu

Affiliation Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SL NQ. Performed the experiments: SL. Analyzed the data: SL NQ MTL. Contributed reagents/materials/analysis tools: SL NQ. Wrote the paper: SL NQ.

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Osteoblasts
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Neural crest
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Osteoblast differentiation
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Frontal bones
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MAPK signaling cascades
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Osteocytes
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Alizarin staining
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Cell proliferation
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