Impaired Function of HDAC6 Slows Down Axonal Growth and Interferes with Axon Initial Segment Development

Mónica Tapia; Francisco Wandosell; Juan José Garrido

doi:10.1371/journal.pone.0012908

Loading metrics

Open Access

Peer-reviewed

Research Article

Impaired Function of HDAC6 Slows Down Axonal Growth and Interferes with Axon Initial Segment Development

Mónica Tapia,

Affiliations Department of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Sevilla, Spain
⨯
Francisco Wandosell,

Affiliations Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Sevilla, Spain
⨯
Juan José Garrido

* E-mail: jjgarrido@cajal.csic.es

Affiliations Department of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Sevilla, Spain
⨯

Impaired Function of HDAC6 Slows Down Axonal Growth and Interferes with Axon Initial Segment Development

Mónica Tapia,
Francisco Wandosell,
Juan José Garrido

Published: September 23, 2010
https://doi.org/10.1371/journal.pone.0012908

About the Authors

Mónica Tapia

Affiliations Department of Molecular, Cellular and Developmental Neurobiology, Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Sevilla, Spain

Francisco Wandosell

Affiliations Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Madrid, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Sevilla, Spain

Juan José Garrido

* E-mail: jjgarrido@cajal.csic.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MT FGW JJG. Performed the experiments: MT. Analyzed the data: MT FGW JJG. Wrote the paper: JJG.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Axons
Is the Subject Area "Axons" applicable to this article?

Thanks for your feedback.
Microtubules
Is the Subject Area "Microtubules" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Tubulins
Is the Subject Area "Tubulins" applicable to this article?

Thanks for your feedback.
Acetylation
Is the Subject Area "Acetylation" applicable to this article?

Thanks for your feedback.
Sodium channels
Is the Subject Area "Sodium channels" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.