The Terminal Immunoglobulin-Like Repeats of LigA and LigB of Leptospira Enhance Their Binding to Gelatin Binding Domain of Fibronectin and Host Cells

Yi-Pin Lin; Sean P. McDonough; Yogendra Sharma; Yung-Fu Chang

doi:10.1371/journal.pone.0011301

Loading metrics

Open Access

Peer-reviewed

Research Article

The Terminal Immunoglobulin-Like Repeats of LigA and LigB of Leptospira Enhance Their Binding to Gelatin Binding Domain of Fibronectin and Host Cells

Yi-Pin Lin,

Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
⨯
Sean P. McDonough,

Affiliation Department of Biomedical Science, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
⨯
Yogendra Sharma,

Affiliation Center for Cellular and Molecular Biology, Hyderabad, India
⨯
Yung-Fu Chang

* E-mail: yc42@cornell.edu

Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
⨯

The Terminal Immunoglobulin-Like Repeats of LigA and LigB of Leptospira Enhance Their Binding to Gelatin Binding Domain of Fibronectin and Host Cells

Yi-Pin Lin,
Sean P. McDonough,
Yogendra Sharma,
Yung-Fu Chang

Published: June 24, 2010
https://doi.org/10.1371/journal.pone.0011301

About the Authors

Yi-Pin Lin

Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Sean P. McDonough

Affiliation Department of Biomedical Science, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Yogendra Sharma

Affiliation Center for Cellular and Molecular Biology, Hyderabad, India

Yung-Fu Chang

* E-mail: yc42@cornell.edu

Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YPL YFC. Performed the experiments: YPL YFC. Analyzed the data: YPL YS YFC. Contributed reagents/materials/analysis tools: SPM YS. Wrote the paper: YPL SPM YFC.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Protein domains
Is the Subject Area "Protein domains" applicable to this article?

Thanks for your feedback.
Cell binding
Is the Subject Area "Cell binding" applicable to this article?

Thanks for your feedback.
Leptospira
Is the Subject Area "Leptospira" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Globular proteins
Is the Subject Area "Globular proteins" applicable to this article?

Thanks for your feedback.
Extracellular matrix proteins
Is the Subject Area "Extracellular matrix proteins" applicable to this article?

Thanks for your feedback.
Chlorides
Is the Subject Area "Chlorides" applicable to this article?

Thanks for your feedback.