About the Authors

Daniel L. J. Thorek

Affiliation Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Patricia Y. Tsao

Affiliation Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Vaishali Arora

Affiliation Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Lanlan Zhou

Affiliation Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Robert A. Eisenberg

Affiliation Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Andrew Tsourkas

atsourk@seas.upenn.edu

Affiliation Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

This work was supported in part by Wyeth-Ayerst Pharmaceuticals. However, all information and materials are freely available in adherence with PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DLJT PT RE AT. Performed the experiments: DLJT PT VA LZ. Analyzed the data: DLJT RE AT. Contributed reagents/materials/analysis tools: DLJT RE AT. Wrote the paper: DLJT RE AT.