14-3-3τ Regulates Beclin 1 and Is Required for Autophagy

Bing Wang; Shiyun Ling; Weei-Chin Lin

doi:10.1371/journal.pone.0010409

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Open Access

Peer-reviewed

Research Article

14-3-3τ Regulates Beclin 1 and Is Required for Autophagy

Bing Wang ,

Contributed equally to this work with: Bing Wang, Shiyun Ling

Affiliation Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Shiyun Ling ,

Contributed equally to this work with: Bing Wang, Shiyun Ling

Affiliations Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Weei-Chin Lin

* E-mail: weeichil@bcm.edu

Affiliations Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯

14-3-3τ Regulates Beclin 1 and Is Required for Autophagy

Bing Wang,
Shiyun Ling,
Weei-Chin Lin

Published: April 29, 2010
https://doi.org/10.1371/journal.pone.0010409

About the Authors

Bing Wang

Contributed equally to this work with: Bing Wang, Shiyun Ling

Affiliation Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

Shiyun Ling

Contributed equally to this work with: Bing Wang, Shiyun Ling

Affiliations Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

Weei-Chin Lin

* E-mail: weeichil@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WCL. Performed the experiments: BW SL. Analyzed the data: BW SL WCL. Contributed reagents/materials/analysis tools: WCL. Wrote the paper: BW SL WCL. Designed the experiments: BW SL.

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Autophagic cell death
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Small interfering RNA
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Transfection
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Gene regulation
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Reverse transcriptase-polymerase chain reaction
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Extracellular matrix proteins
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Gene expression
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Hepatocellular carcinoma
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