About the Authors

Tamaryn J. Cashmore

Contributed equally to this work with: Tamaryn J. Cashmore, Jonathan G. Peter

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Jonathan G. Peter

Contributed equally to this work with: Tamaryn J. Cashmore, Jonathan G. Peter

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Richard N. van Zyl-Smit

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Patricia L. Semple

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Alice Maredza

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Richard Meldau

Affiliation Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa

Alimuddin Zumla

Affiliation Centre for Infectious Diseases and International Health, Department of Infection, UCL Medical School, London, United Kingdom

Barbara Nurse

Affiliation Department of Clinical Laboratory Sciences, National Health Laboratory Service/University of Cape Town, Cape Town, South Africa

Keertan Dheda

keertan.dheda@uct.ac.za

Affiliations Lung Infection and Immunity Unit, Division of Pulmonology, UCT Lung Institute and Clinical Immunology, Department of Medicine, University of Cape Town, Cape Town, South Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa, Centre for Infectious Diseases and International Health, Department of Infection, UCL Medical School, London, United Kingdom

Competing Interests

Dr Keertan Dheda is on one PLoS ONE editorial board. The authors have no further competing interests.

Author Contributions

Conceived and designed the experiments: TJC JP AZ KD. Performed the experiments: TJC JP RM. Analyzed the data: TJC JP RvZS PLS KD. Contributed reagents/materials/analysis tools: BN KD. Wrote the paper: TJC JP. Oversaw laboratory experiments: KD. Preparation of the manuscript: KD, RvZS, PLS, AM, BN. Assistance with statistics: RvZS, PLS. Assisted with laboratory experiments: RM. Supervision of laboratory services: BN.