About the Authors

Michael V. Holmes

Affiliation King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, United Kingdom

Benyu Jiang

Affiliation King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, United Kingdom

Karen McNeill

Affiliation King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, United Kingdom

Melinda Wong

Current address: Department of Rheumatology, St. Vincent's Hospital, Melbourne, Australia

Affiliation King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, United Kingdom

Stephen P. Oakley

Current address: Department of Rheumatology, Royal Newcastle Centre, Newcastle, Australia

Affiliation Department of Rheumatology, Guy's and St. Thomas' National Health Service Foundation Trust, London, United Kingdom

Bruce Kirkham

Affiliations Department of Rheumatology, Guy's and St. Thomas' National Health Service Foundation Trust, London, United Kingdom, National Institute for Health Research, Guy's and St. Thomas' National Health Service Foundation Trust, King's College London Biomedical Research Centre, London, United Kingdom

Phil J. Chowienczyk

phil.chowienczyk@kcl.ac.uk

Affiliation King's College London, British Heart Foundation Centre, Department of Clinical Pharmacology, St. Thomas' Hospital, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MW SPO BK PC. Performed the experiments: MW BJ KM. Analyzed the data: MVH PC. Contributed reagents/materials/analysis tools: MVH PC. Wrote the paper: MVH PC.