About the Authors

Luke H. Bradley

lhbradley@uky.edu

Affiliations Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America, Department of Molecular & Cellular Biochemistry and the Center of Structural Biology, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Josh Fuqua

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

April Richardson

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Jadwiga Turchan-Cholewo

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Yi Ai

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Kristen A. Kelps

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

John D. Glass

Affiliation Shoreham, New York, United States of America

Xiuquan He

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Zhiming Zhang

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Richard Grondin

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

O. Meagan Littrell

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Peter Huettl

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Francois Pomerleau

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Don M. Gash

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Greg A. Gerhardt

Affiliation Department of Anatomy & Neurobiology and the Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America

Competing Interests

L.H.B., J.D.G., D.M.G., and G.A.G. declare that 3 patents are pending regarding findings reported in the manuscript. These potential competing interests do not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LHB JF AR JTC YA KAK JDG ZZ RG PH FP DMG GG. Performed the experiments: LHB JF AR JTC YA KAK XH OML. Analyzed the data: LHB JF AR JTC YA KAK JDG XH ZZ RG OML PH FP DMG GG. Contributed reagents/materials/analysis tools: LHB JDG DMG GG. Wrote the paper: LHB JF AR JTC YA KAK PH FP DMG GG.