About the Authors

Louise S. Harrington

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom

Laura Moreno

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom

Anna Reed

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom

Stephen J. Wort

Affiliation Critical Care Medicine, NHLI, Royal Brompton Hospital, London, United Kingdom

Béatrice Desvergne

Affiliation Center for Integrative Genomics, University of Lausanne, Genopode, Lausanne, Switzerland

Christopher Garland

Affiliation Department of Pharmacology, University of Oxford, Oxford, United Kingdom

Lan Zhao

Affiliation Experimental Medicine and Toxicology, Hammersmith Hospital, Imperial College London, London, United Kingdom

Jane A. Mitchell

j.a.mitchell@ic.ac.uk

Affiliation Cardiothoracic Pharmacology, NHLI, Imperial College London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LH LM AR LZ JAM. Performed the experiments: LH LM AR CG LZ. Analyzed the data: LH LM AR CG LZ. Contributed reagents/materials/analysis tools: BD. Wrote the paper: AR JAM. Contributed to the writing of the paper: LH LM. Contributed to the overall study design and interpretation of data: SJW.