About the Authors
- Sandipan Chatterjee
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Current address: 3-V Biosciences, Schlieren, Switzerland
Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
- Joseph D. Szustakowski
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
- Nirmala R. Nanguneri
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
- Craig Mickanin
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
- Mark A. Labow
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
- Axel Nohturfft
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Affiliation Division of Basic Medical Sciences, St. George's University of London, London, United Kingdom
- Kumlesh K. Dev
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* E-mail: devk@tcd.ie (KKD); rajeev.sivasankaran@novartis.com (RS)
Current address: Molecular Neuropharmacology, Department of Physiology, Trinity College Institute of Neuroscience, Dublin, Ireland
Affiliation Department of Anatomy, University College Cork, Cork, Ireland
- Rajeev Sivasankaran
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* E-mail: devk@tcd.ie (KKD); rajeev.sivasankaran@novartis.com (RS)
Affiliation Developmental and Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America
Competing Interests
We have a patent filed relating to some of the material that is presented in the manuscript: (WO/2007/141346) GENES REGULATING INTRACELLULAR CHOLESTEROL TRAFFICKING AS TARGETS FOR TREATMENT OF CHOLESTEROL-RELATED DISEASES. SC, JDS, NRM, CM, MAL and RS are employed by Novartis.
Author Contributions
Conceived and designed the experiments: SC AN KD RS. Performed the experiments: SC. Analyzed the data: SC KD RS. Contributed reagents/materials/analysis tools: AN. Wrote the paper: SC RS. Conceived and performed the GSEA analysis: JS NN. Provided high throughput screening expertise: CM ML.