About the Authors

Basarab G. Hosu

Affiliation Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

Steven F. Mullen

sfm5ff@mizzou.edu

Affiliation 21st Century Medicine, Fontana, California, United States of America

John K. Critser

Affiliation Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America

Gabor Forgacs

Affiliations Department of Biological Sciences, University of Missouri, Columbia, Missouri, United States of America, Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America, Department of Physics, University of Missouri, Columbia, Missouri, United States of America

Competing Interests

A provisional patent application was filed in November 2007 with the US Patent and Trademark Office (USPTO) concerning the use of chemical compounds to depolymerize the cell cytoskeleton as a method that minimizes damage to cells during cryopreservation due to physical factors associated with the cell's cytoskeletal network. No licensing agreements have been established to date.

Author Contributions

Conceived and designed the experiments: BGH SFM JKC GF. Performed the experiments: BGH SFM. Analyzed the data: BGH SFM JKC GF. Contributed reagents/materials/analysis tools: BGH. Wrote the paper: BGH SFM JKC GF.