About the Authors

Jianxu Li

Contributed equally to this work with: Jianxu Li, Hongbing Wu, Jing Hong

Affiliations Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

Hongbing Wu

Contributed equally to this work with: Jianxu Li, Hongbing Wu, Jing Hong

Affiliation School of Pharmacy, Fudan University, Shanghai, China

Jing Hong

Contributed equally to this work with: Jianxu Li, Hongbing Wu, Jing Hong

Affiliations Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

Xueqing Xu

Affiliations Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

Hailong Yang

Affiliation Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan, China

Bingxian Wu

Affiliation School of Pharmacy, Fudan University, Shanghai, China

Yipeng Wang

Affiliations Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

Jianhua Zhu

Affiliation School of Pharmacy, Fudan University, Shanghai, China

Ren Lai

rlai@mail.kiz.ac.cn (RL); xgjiang@shmu.edu.cn (XJ); dhlin@mail.shcnc.ac.cn (DL)

Affiliation Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan, China

Xinguo Jiang

rlai@mail.kiz.ac.cn (RL); xgjiang@shmu.edu.cn (XJ); dhlin@mail.shcnc.ac.cn (DL)

Affiliation School of Pharmacy, Fudan University, Shanghai, China

Donghai Lin

rlai@mail.kiz.ac.cn (RL); xgjiang@shmu.edu.cn (XJ); dhlin@mail.shcnc.ac.cn (DL)

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Mark C. Prescott

Affiliation School of Biological Sciences University of Liverpool, Liverpool, United Kingdom

Huw H. Rees

Affiliation School of Biological Sciences University of Liverpool, Liverpool, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RL XJ DL. Performed the experiments: XX JL YW HW HY BW JZ MP JH. Analyzed the data: RL XX HR JL YW HW HY BW JZ XJ DL MP JH. Contributed reagents/materials/analysis tools: RL. Wrote the paper: RL HR JL HW XJ DL JH.