Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes

Stein Aerts; Jacques van Helden; Olivier Sand; Bassem A. Hassan

doi:10.1371/journal.pone.0001115

Loading metrics

Open Access

Peer-reviewed

Research Article

Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes

Stein Aerts ,

*To whom correspondence should be addressed. E-mail: stein.aerts@med.kuleuven.be (SA); bassem.hassan@med.kuleuven.be (BH)

Affiliations Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium, Department of Human Genetics, K.U. Leuven School of Medicine, Leuven, Belgium
⨯
Jacques van Helden,

Affiliation Service de Conformation des Macromolécules Biologiques et de Bioinformatique, Département de Biologie Moléculaire, Université Libre de Bruxelles, Bruxelles, Belgium
⨯
Olivier Sand,

Affiliation Service de Conformation des Macromolécules Biologiques et de Bioinformatique, Département de Biologie Moléculaire, Université Libre de Bruxelles, Bruxelles, Belgium
⨯
Bassem A. Hassan

*To whom correspondence should be addressed. E-mail: stein.aerts@med.kuleuven.be (SA); bassem.hassan@med.kuleuven.be (BH)

Affiliations Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium, Department of Human Genetics, K.U. Leuven School of Medicine, Leuven, Belgium
⨯

Fine-Tuning Enhancer Models to Predict Transcriptional Targets across Multiple Genomes

Stein Aerts,
Jacques van Helden,
Olivier Sand,
Bassem A. Hassan

Published: November 7, 2007
https://doi.org/10.1371/journal.pone.0001115

About the Authors

Stein Aerts

*To whom correspondence should be addressed. E-mail: stein.aerts@med.kuleuven.be (SA); bassem.hassan@med.kuleuven.be (BH)

Affiliations Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium, Department of Human Genetics, K.U. Leuven School of Medicine, Leuven, Belgium

Jacques van Helden

Affiliation Service de Conformation des Macromolécules Biologiques et de Bioinformatique, Département de Biologie Moléculaire, Université Libre de Bruxelles, Bruxelles, Belgium

Olivier Sand

Affiliation Service de Conformation des Macromolécules Biologiques et de Bioinformatique, Département de Biologie Moléculaire, Université Libre de Bruxelles, Bruxelles, Belgium

Bassem A. Hassan

*To whom correspondence should be addressed. E-mail: stein.aerts@med.kuleuven.be (SA); bassem.hassan@med.kuleuven.be (BH)

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SA. Performed the experiments: Jv SA OS. Analyzed the data: SA. Contributed reagents/materials/analysis tools: Jv OS. Wrote the paper: BH SA.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Invertebrate genomics
Is the Subject Area "Invertebrate genomics" applicable to this article?

Thanks for your feedback.
Sequence motif analysis
Is the Subject Area "Sequence motif analysis" applicable to this article?

Thanks for your feedback.
Drosophila melanogaster
Is the Subject Area "Drosophila melanogaster" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Network motifs
Is the Subject Area "Network motifs" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Gene ontologies
Is the Subject Area "Gene ontologies" applicable to this article?

Thanks for your feedback.