Feasibility, acceptability and effectiveness of digitally delivered multimodal prehabilitation for cancer patients: A mixed-methods systematic review

Jeremiah Oyedemi, Simon Dunne, Louise Brennan, Laura Coffey

PLOS Digital Health: published March 2, 2026 | https://doi.org/10.1371/journal.pdig.0001258

Association between deep learning–based atrial fibrillation burden and in-hospital mortality

Yongseop Lee, Yujee Chang, Jihoon Seo, Jung Ah Lee, Jung Ho Kim, Jin Young Ahn, Su Jin Jeong, Jun Yong Choi, Joon-Sup Yeom, Nam Su Ku, Dukyong Yoon

PLOS Digital Health: published March 4, 2026 | https://doi.org/10.1371/journal.pdig.0001266

Functional connectivity–based classification and subtyping of major depression for precision mental health: An ensemble graph neural network approach

Kaizhong Zheng, Hongbing Lu, Huaning Wang, Dewen Hu, Badong Chen, Baojuan Li

PLOS Digital Health: published March 4, 2026 | https://doi.org/10.1371/journal.pdig.0001261

Heterogeneous associations of a mobile health-based disease management program on uncontrolled hypertension: A target trial emulation study

Masashi Kanai, Takahiro Miki, Takuya Toda, Yuta Hagiwara, Takaaki Ikeda

PLOS Digital Health: published March 5, 2026 | https://doi.org/10.1371/journal.pdig.0001268

SynthCraft: An AI partner for synthetic data generation to support data access and augmentation in healthcare

Thomas Callender, Anders Boyd, Robert Davis, Silas Ruhrberg Estevez, Juan M. Lavista Ferres, Mihaela van der Schaar

PLOS Digital Health: published March 9, 2026 | https://doi.org/10.1371/journal.pdig.0001290

Real-world effects of alcohol on heart rate, sleep, and physical activity by age and sex

Gregory J. Grosicki, Austin T. Robinson, Michael J. Joyner, Jason R. Carter, William von Hippel, David M. Presby, Finnbarr Fielding, Jeremy A. Bigalke, Jeongeun Kim, Christopher Chapman, Kristen E. Holmes

PLOS Digital Health: published March 9, 2026 | https://doi.org/10.1371/journal.pdig.0001284

The adaptive large language models for vaccine prediction: A novel approach to vaccine demand prediction with engineered deviation prompts

Mingming Chen, Qiangsong Wu, Zilong Wang, Qi Qi, Yi Hu, Tenglong Li

PLOS Digital Health: published March 9, 2026 | https://doi.org/10.1371/journal.pdig.0001273

How exclusion criteria can hinder eligibility for lung cancer studies among different racial and ethnic groups

Jennifer Y. Kim, Abigail Dirks, Ruby Madison Ford, Lori Pai, Calvin Ludwig, Umit Tapan

PLOS Digital Health: published March 10, 2026 | https://doi.org/10.1371/journal.pdig.0001262

Efficient information extraction using LLMs and knowledge distillation: A study on HPV health communication

Saadat Hasan Khan, Kevin Lybarger

PLOS Digital Health: published March 10, 2026 | https://doi.org/10.1371/journal.pdig.0001275

Real World Human-LLM Interactions – Prospective blinded versus unblinded expert physician assessments of LLM responses to complex medical dilemmas

Itamar Ben Shitrit, Daphna Idan, Mark Volevich, Hadar Sharabi Goldenberg, Dolev Vaknin, Or Degany, Nitzan Abelson, Yair Binyamin, Raouf Nassar, Majd Nassar, Aviya Kedmi, Alexander Zlotnik, Sharon Einav

PLOS Digital Health: published March 12, 2026 | https://doi.org/10.1371/journal.pdig.0001278

Advancing the science of qualitative patient preference assessment using large language models

Ted Grover, Emanuel Krebs, Deirdre Weymann, Morgan Ehman, Dean A. Regier

PLOS Digital Health: published March 12, 2026 | https://doi.org/10.1371/journal.pdig.0001263

Cardiology knowledge assessment of retrieval-augmented open versus proprietary large language models

Constantine Tarabanis, Shaan Khurshid, Areti Karamanou, Rodo Piperaki, Lucas A. Mavromatis, Aris Hatzimemos, Dimitrios Tachmatzidis, Constantinos Bakogiannis, Vassilios Vassilikos, Patrick T. Ellinor, Lior Jankelson, Evangelos Kalampokis

PLOS Digital Health: published March 12, 2026 | https://doi.org/10.1371/journal.pdig.0001029

Interpretable machine learning for predicting delays in seeking abortion among reproductive-aged women in Ethiopia: A study using EDHS 2016 data

Meron Asmamaw Alemayehu, Almaw Genet Yeshiwas, Abebaw Molla Kebede, Habitamu Mekonen, Getaneh Atikilt Yemata, Amare Genetu Ejigu, Ahmed Fentaw Ahmed, Abathun Temesgen, Gashaw Melkie Bayeh, Chalachew Yenew, Rahel Mulatie Anteneh, Zeamanuel Anteneh Yigzaw, Fantu Mamo Aragaw, Getasew Yirdaw, Sintayehu Simie Tsega, Anley Shiferaw Enawgaw, Tilahun Degu Tsega, Zufan Alamrie Asmare, Berhanu Abebaw Mekonnen

PLOS Digital Health: published March 13, 2026 | https://doi.org/10.1371/journal.pdig.0001288

“It could bring a lot of help to people that aren’t getting help right now”: A qualitative analysis of the impact of virtual care on access to primary care for people with opioid use disorder

Shawna Narayan, Sarah Spencer, Lindsay Hedden, Ellie Gooderham, Sarah Muñoz-Violant, Rita K. McCracken

PLOS Digital Health: published March 17, 2026 | https://doi.org/10.1371/journal.pdig.0001299

Evaluating the impact of discordant and missing demographic information on population health assessments using linked electronic health records and Census Bureau microdata

Derek Ouyang, Aubrey Limburg, David H. Rehkopf, Jacob Goldin, Robert L. Phillips, Victoria Udalova, Daniel E. Ho

PLOS Digital Health: published March 17, 2026 | https://doi.org/10.1371/journal.pdig.0001289

Using supermarket loyalty card data to investigate seasonal variation in laxative purchases in the UK

Romana Burgess, Neo Poon, Edward Sloan, James Goulding, Helen Bould, Anya Skatova

PLOS Digital Health: published March 18, 2026 | https://doi.org/10.1371/journal.pdig.0000963

Visual recognition limitations in multimodal large language models: A comparative analysis of histological image interpretation

Volodymyr Mavrych, Einas M. Yousef, Ahmed Yaqinuddin, Aftab Ahmed Shaikh, Olena Bolgova

PLOS Digital Health: published March 19, 2026 | https://doi.org/10.1371/journal.pdig.0001306

Explainable artificial intelligence for personalized prognosis in pancreatic cancer: A nationwide study from Taiwan

Dai-Rong Tsai, Chun-Ju Chiang, Pei-Chun Hsieh, Chi-Yen Huang, Wen-Chung Lee

PLOS Digital Health: published March 19, 2026 | https://doi.org/10.1371/journal.pdig.0001296

Participatory-informed preference optimization (PiPrO): A reinforcement learning simulation study

Tara Templin, Shuyi Song, Sophia Fort, Nasa Sinnott-Armstrong

PLOS Digital Health: published March 19, 2026 | https://doi.org/10.1371/journal.pdig.0001294

What should be included in a digital mental health intervention, based on solution-focused therapy, for young people who self-harm? A qualitative exploration of young people and clinicians’ views

Lauren Jerome, Katherine Adams, Victoria Bird, Dennis Ougrin

PLOS Digital Health: published March 20, 2026 | https://doi.org/10.1371/journal.pdig.0001276

Characterizing patients who benefit from mature medical AI models in real-world clinical applications

Zhiyi Chen, Wei Li, Zhicheng Lin

PLOS Digital Health: published March 20, 2026 | https://doi.org/10.1371/journal.pdig.0001283

Impact of electronic health records on nursing workflow efficiency and predictive factors in Palestinian hospitals

Fuad Farajalla, Mousa Farajallah, Nesreen Alqaissi, Mohammad Qtait, Zeenat Mousa Mesk

PLOS Digital Health: published March 20, 2026 | https://doi.org/10.1371/journal.pdig.0001318

Clustering of disease trajectories with explainable machine learning: A case study on postoperative delirium phenotypes

Xiaochen Zheng, Ahmed Allam, Manuel Schürch, Xingyu Chen, Maria Angeliki Komninou, Reto Schüpbach, Jan Bartussek, Michael Krauthammer

PLOS Digital Health: published March 23, 2026 | https://doi.org/10.1371/journal.pdig.0001267

A problem of Epic proportion

Rawan Abulibdeh, Matthew G. Crowson, Molly J. Douglas, Mena Ramos, Noelle N. Saillant, Leo Anthony Celi

PLOS Digital Health: published March 23, 2026 | https://doi.org/10.1371/journal.pdig.0001143

SpiroLLM: Finetuning pretrained LLMs to understand spirogram time series with clinical validation in COPD reporting

Shuhao Mei, Yongchao Long, Xiaoyu Xiao, Shan Cao, Xiaobo Han, Shijia Geng, Jinbo Sun, Yuxi Zhou, Shenda Hong

PLOS Digital Health: published March 24, 2026 | https://doi.org/10.1371/journal.pdig.0001300

Performance of predictive AI-based clinical decision support systems across clinical domains: A systematic review and meta-analysis

William J. Waldock, Ahmad Guni, Ara Darzi, Hutan Ashrafian

PLOS Digital Health: published March 24, 2026 | https://doi.org/10.1371/journal.pdig.0001310

Improvements in blood and fitness tracker biomarkers in a longitudinal real-world cohort of digital health platform users

Nimisha Schneider, Paul Fabian, Michelle Cawley, Bartek Nogal, Gil Blander, Renee Deehan

PLOS Digital Health: published March 24, 2026 | https://doi.org/10.1371/journal.pdig.0001271

Patterns of smartphone typing performance by time awake: implications for unobtrusive ambulatory mental fatigue assessment

Yu Fang, Peter Yang, Elena Frank, Cathy Goldstein, Aidan G. C. Wright, Amy S. B. Bohnert, Vik Kheterpal, Srijan Sen, Zhenke Wu

PLOS Digital Health: published March 26, 2026 | https://doi.org/10.1371/journal.pdig.0001281

Safeguarding patient privacy in eHealth systems: Bridging theory and practice through a scoping review and healthcare survey

Michael Winter, Robin Kraft, Celine Belas, Manfred Reichert, Maximilian Ertl, Rüdiger Pryss

PLOS Digital Health: published March 26, 2026 | https://doi.org/10.1371/journal.pdig.0001325

Privacy concerns regarding personal health information in Myanmar: A cross-sectional survey in a least developed country

Khaing Zin Zin Htwe, Saranath Lawpoolsri, Ngamphol Soonthornworasiri, Panithee Thammawijaya, Jaranit Kaewkungwal

PLOS Digital Health: published March 26, 2026 | https://doi.org/10.1371/journal.pdig.0001007

AVPENet: Pain estimation from audio-visual fusion of non-speech sounds

Sami Naouali, Oussama El Othmani

PLOS Digital Health: published March 27, 2026 | https://doi.org/10.1371/journal.pdig.0001301

Vascular age estimation using a consumer wearable sleep tracker

Gizem Yilmaz, Shohreh Ghorbani, Ju Lynn Ong, Hosein Aghayan Golkashani, Chen Zhang, B. T. Thomas Yeo, Michael W. L. Chee

PLOS Digital Health: published March 30, 2026 | https://doi.org/10.1371/journal.pdig.0001329

Large language model detects previously undiagnosed heart failure with preserved ejection fraction in patients with metabolic-associated fatty liver disease: A multicenter cohort study

Xiaodan Lu, Xuliang Wang, Da Liu, Zhiyuan Zhang, Yuqiang Zhang, Tiancheng Zhang, Di Lu, Shengli Kuang, Chunjin Lai, Fushi Piao, Min Lin, Shengsong Zhu, Zhuchang Tian, Wei Fu, Yongbin Dai, Chengli Yao, Gang Li, Zhenzhong Zheng, Xiangbin Meng, Hongxing Luo

PLOS Digital Health: published March 31, 2026 | https://doi.org/10.1371/journal.pdig.0001317

3D-ViT-UNet: 3D Vision transformer based Unet-like model for Volumetric Brain Tumor Segmentation

Sikandar Afridi, Atif Jan, Muhammad Abeer Irfan, Muhammad Irfan Khattak, Taimur Ahmed Khan

PLOS Digital Health: published March 31, 2026 | https://doi.org/10.1371/journal.pdig.0001323

Tracking daily activities with ecological momentary assessment: A bibliometric analysis of current use in health Mapping daily activities with ecological momentary assessment

Eva Delooz, Bruno Bonnechère, Barbara Piškur, Annemie Spooren

PLOS Digital Health: published March 31, 2026 | https://doi.org/10.1371/journal.pdig.0001331

Autism data sharing: Benefits, challenges, and recommendations

Alexandra Lautarescu, Brett Trost, Azadeh Kushki, Bethany Oakley, Síofra Heraty, David Belton, Alison Boyle, Sarah Douglas, Ciara J. Molloy, Rosemary Holt, Madeleine Bloomfield, Florence Campana, Miro Cupak, Erica Stevenson, Julian Tillmann, Christopher Chatham, Evdokia Anagnostou, Dean Hartley, Tony Charman

PLOS Digital Health: published March 2, 2026 | https://doi.org/10.1371/journal.pdig.0001249

Recent advances in corneal specular microscopy image analysis through artificial intelligence

Andres G. Marrugo, Fernando Quintero, Alejandro Tello, Angélica M. Prada, Virgilio Galvis, Lenny A. Romero

PLOS Digital Health: published March 31, 2026 | https://doi.org/10.1371/journal.pdig.0001305

Correction: A feature-based qualitative assessment of smoking cessation mobile applications

Lydia Tesfaye, Michael Wakeman, Gunnar Baskin, Greg Gruse, Tim Gregory, Erin Leahy, Brandon Kendrick, Sherine El-Toukhy

PLOS Digital Health: published March 19, 2026 | https://doi.org/10.1371/journal.pdig.0001307

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Empowering the nursing workforce for cyber-resilience: Strategic preparedness and care management during hospital cyberattacks

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