A multi-agent approach to neurological clinical reasoning

Moran Sorka, Alon Gorenshtein, Dvir Aran, Shahar Shelly

PLOS Digital Health: published December 4, 2025 | https://doi.org/10.1371/journal.pdig.0001106

Developing and validating an explainable digital mortality prediction tool for extremely preterm infants

T’ng Chang Kwok, Chao Chen, Jayaprakash Veeravalli, Carol A.C. Coupland, Edmund Juszczak, Jonathan Garibaldi, Kirsten Mitchell, Kate L. Francis, Christopher J. D. McKinlay, Brett J. Manley, Don Sharkey

PLOS Digital Health: published December 10, 2025 | https://doi.org/10.1371/journal.pdig.0000955

The Healthy Environments and Active Living for Translational Health (HEALTH) Platform: A smartphone-based system for geographic ecological momentary assessment research

Alexander J. Wray, Katelyn R. O’Bright, Shiran Zhong, Sean Doherty, Michael Luubert, Jed Long, Catherine E. Reining, Christopher J. Lemieux, Jon Salter, Jason Gilliland

PLOS Digital Health: published December 11, 2025 | https://doi.org/10.1371/journal.pdig.0001133

COVID-19 vaccination data management and visualization systems for improved decision-making: Lessons learnt from Africa CDC Saving Lives and Livelihoods program

Raji Tajudeen, Mosoka Papa Fallah, John Ojo, Tamrat Shaweno, Michael Sileshi Mekbib, Frehiwot Mulugeta, Wondwossen Amanuel, Moses Bamatura, Dennis Kibiye, Patrick Chanda Kabwe, Senga Sembuche, Ngashi Ngongo, Nebiyu Dereje, Jean Kaseya

PLOS Digital Health: published December 11, 2025 | https://doi.org/10.1371/journal.pdig.0000782

Telemedicine in adult intensive care: A systematic review of patient-relevant outcomes and methodological considerations

Tamara Pscheidl, Carina Benstoem, Kelly Ansems, Lena Saal-Bauernschubert, Anne Ritter, Ana-Mihaela Zorger, Karolina Dahms, Sandra Dohmen, Eva Steinfeld, Julia Dormann, Claire Iannizzi, Nicole Skoetz, Heidrun Janka, Maria-Inti Metzendorf, Carla Nau, Miriam Stegemann, Patrick Meybohm, Falk von Dincklage, Sven Laudi, Falk Fichtner, Stephanie Weibel

PLOS Digital Health: published December 15, 2025 | https://doi.org/10.1371/journal.pdig.0001126

A novel expert-annotated single-cell dataset for thyroid cancer diagnosis with deep learning benchmarks

Nguyen Quang Huy, Thanh-Ha Do, Nguyen Van De, Hoang Kim Giap, Vu Huyen Tram

PLOS Digital Health: published December 16, 2025 | https://doi.org/10.1371/journal.pdig.0001120

Towards precision psychiatry: Metabolomics identifies three biological subtypes of depression

Simeng Ma, Zhaowen Nie, Mengyuan Zhang, Junhua Mei, Enqi Zhou, Zhiyi Hu, Honggang Lv, Qian Gong, Gaohua Wang, Huiling Wang, Bo Du, Jun Yang, Zhongchun Liu

PLOS Digital Health: published December 19, 2025 | https://doi.org/10.1371/journal.pdig.0001125

AI-assisted assessment of the IFSO consensus on obesity management medications in the context of metabolic bariatric surgery

Mohammad Kermansaravi, Paulina Salminen, Gerhard Prager, Ricardo V. Cohen

PLOS Digital Health: published December 19, 2025 | https://doi.org/10.1371/journal.pdig.0001132

Evaluating ChatGPT-4 in the development of family medicine residency examinations

Hanu Chaudhari, Christopher Meaney, Kulamakan Kulasegaram, Fok-Han Leung

PLOS Digital Health: published December 19, 2025 | https://doi.org/10.1371/journal.pdig.0001156

Implementation of large language models in electronic health records

Maxime Griot, Jean Vanderdonckt, Demet Yuksel

PLOS Digital Health: published December 19, 2025 | https://doi.org/10.1371/journal.pdig.0001141

Integrating intramuscular fat radiomics with hamstrings-to-quadriceps structure and function ratios to predict future hamstring strain injury

Akanksha Sharma, Daniel R. Smith, Alexis B. Slutsky-Ganesh, Jed A. Diekfuss, Jennifer A. Hogg, Kim D. Barber Foss, Christopher D. Riehm, Augustin C. Ogier, Constance P. Michel, David Bendahan, Richard Danilkowicz, Joseph Lamplot, Destin Hill, Kyle Hammond, Charles Kenyon, Gregory D. Myer, Anant Madabhushi

PLOS Digital Health: published December 23, 2025 | https://doi.org/10.1371/journal.pdig.0001144

Autism spectrum disorder detection using diffusion tensor imaging and machine learning

Noel A. Cardenas-Hernandez, Marlen Perez-Diaz, Karla Batista García-Ramó, Maria del C. Valdés Hernández

PLOS Digital Health: published December 23, 2025 | https://doi.org/10.1371/journal.pdig.0001155

Towards responsible surveillance in preventive health data-AI research

Sam H. A. Muller, Johannes J. M. van Delden, Ghislaine J. M. W. van Thiel, Hypermarker Consortium

PLOS Digital Health: published December 29, 2025 | https://doi.org/10.1371/journal.pdig.0001146

Examining Canadian youth’s engagement with food companies via digital media

Laura Vergeer, Meghan Pritchard, Carolina Soto, Elise Pauzé, Ashley Amson, Dana Lee Olstad, Monique Potvin Kent

PLOS Digital Health: published December 30, 2025 | https://doi.org/10.1371/journal.pdig.0001167

Interaction with SMS text-reminders correlate with improved medication adherence and readmission rates for congestive heart failure patients: A retrospective cohort study

Ben Long, Brian Davis, Rebekah McPheters, Steven Burton, Nabeel Hamoud, Dan Garmat, Suzanne Catalfomo, Fei Li, Ying Zhou, Yan L. Zhuang, Colin A. Banas, Weston W. Blakeslee

PLOS Digital Health: published December 31, 2025 | https://doi.org/10.1371/journal.pdig.0001157

Correction: Opportunistic use of artificial intelligence with X-ray imaging for diagnosis of HIV status in tuberculosis patients in Uganda and Tanzania

The PLOS One Staff

PLOS Digital Health: published December 23, 2025 | https://doi.org/10.1371/journal.pdig.0001164

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Correction: Eliminating the AI digital divide by building local capacity

Freya Gulamali, Jee Young Kim, Kartik Pejavara, Ciera Thomas, Varoon Mathur, Zev Eigen, Mark Lifson, Manesh Patel, Keo Shaw, Danny Tobey, Alexandra Valladares, David Vidal, Jared Augenstein, Ashley Beecy, Sofi Bergkvist, Michael Burns, Michael Draugelis, Jesse M. Ehrenfeld, Patricia Henwood, Tonya Jagneaux, Morgan Jeffries, Christopher Khoury, Frank J. Liao, Vincent X. Liu, Chris Longhurst, Dominic Mack, Thomas M. Maddox, David McSwain, Steve Miff, Corey Miller, Sara G. Murray, Brian W. Patterson, Philip Payne, W. Nicholson Price II, Ram Rimal, Michael J. Sheppard, Karandeep Singh, Abdoul Sosseh, Jennifer Stoll, Corinne Stroum, Yasir Tarabichi, Sylvia Trujillo, Ladd Wiley, Alifia Hasan, Joan S. Kpodzro, Suresh Balu, Mark P. Sendak

PLOS Digital Health: published December 30, 2025 | https://doi.org/10.1371/journal.pdig.0001173

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From artificial to organic: Rethinking the roots of intelligence for digital health

Prajwal Ghimire, Keyoumars Ashkan

PLOS Digital Health: published December 1, 2025 | https://doi.org/10.1371/journal.pdig.0001109