Citation: Lokmic-Tomkins Z, Abadi A, Benmarhnia T, Chen K, Chong KC, Conte Keivabu R, et al. (2026) Climate and health at a critical juncture. PLOS Clim 5(4): e0000895. https://doi.org/10.1371/journal.pclm.0000895
Published: April 15, 2026
Copyright: © 2026 Lokmic-Tomkins et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: The authors received no specific funding for this work.
Competing interests: JM is the Executive Editor of PLOS Climate. All other authors are members of the PLOS Climate editorial board.
Introduction
The climate crisis is an ongoing environmental, social, and health equity threat multiplier that poses serious harm to public and planetary health. Over the past two decades, climate-related disasters have increased, with heatwaves, floods, droughts, severe storms, and wildfires affecting over 4 billion people and causing the death of over 1.2 million people globally [1]. Heatwave exposure contributes to nearly half a million deaths each year [2], while climate-sensitive diseases such as dengue, chikungunya, malaria, foodborne and waterborne infections are expanding into new regions, including non-endemic areas, due to improved habitat suitability [3–5]. Health systems, particularly in low- and middle-resource settings, are being overwhelmed by the combined pressures of climate disruption, conflicts and political uncertainty, demographic change, and ensuing economic instability. The economic burden of climate-related health impacts has already reached hundreds of billions of dollars annually and is projected to rise steeply if mitigation and adaptation remain insufficient [6].
These trends are unfolding within a fragile geopolitical landscape. Climate finance commitments remain unmet, multilateral cooperation is strained, and political polarization increasingly challenges the credibility of science and evidence-based policymaking. Yet amid this uncertainty, there are signs of progress. Health is gaining recognition within climate negotiations, with more countries integrating health into national adaptation plans and health service delivery frameworks [6]. Funding for transdisciplinary and interdisciplinary climate–health research is growing [7,8]. This moment is therefore defined by both risk and opportunity. Admittedly, the scale of the challenge is sobering, but so too is the growing recognition that health can serve as a unifying lens for climate action. Rigorous, transdisciplinary and interdisciplinary, and action-oriented climate-health research is foundational to mitigation, adaptation, and resilience. This Editorial sets out a collective direction and a shared commitment, across disciplines, geographies, and generations, to advance climate-health scholarship that is scientifically robust, socially just, and grounded in real-world impact.
Why transdisciplinary and interdisciplinary science is essential
Meeting the scale and complexity of climate-induced health risks demands a new approach to knowledge production, translation, and implementation. The climate-health nexus cannot be understood nor addressed through a single disciplinary lens [8]. It requires an integrative approach across disciplines and methodological tools. Climate and data sciences are needed to provide projections, climate services, and early warnings, while biosciences illuminate physiological vulnerabilities. Social sciences, particularly the community-engaged qualitative approaches, can reveal how inequality, power, and lived experience shape exposure, resilience, and the implementation of interventions. Economics clarifies trade-offs and the costs of inaction, while governance studies enable the interrogation of accountability and institutional design. Demography helps us understand how various changes in population structure (such as birth rate, age ratio, migration) are impacted by climate-related risks, and how future climate risks will impact future populations. Climate change influences biogeochemical cycling of chemical contaminants which then leads to higher community exposure [8,9]. Without collaboration across these and other relevant disciplines (psychology, behavioural science, engineering…), any subsequent intervention will struggle in implementation and sustainability [10,11].
Transdisciplinary engagement with practitioners, policymakers, community leaders and advocacy groups is also essential for effective action. Those on the front lines of climate-related harm possess practical knowledge about what reduces risk in their local environments and what does not. Indigenous and traditional knowledge systems offer context-specific adaptation strategies refined over generations that are yet to be meaningfully integrated into dominant Western knowledge paradigms [3]. A genuine commitment to bottom-up approaches strengthens both legitimacy and effectiveness but also means that policies are more likely to be equitable and more likely to address unmet needs.
Achieving this integration requires moving beyond siloed research cultures and short-term project cycles toward sustained collaboration across sectors and borders. It calls for epistemic humility, sustained engagement beyond funding cycles, openness to multiple ways of knowing, and an explicit commitment to equity in whose voices are heard. Climate change is a systemic crisis reshaping the foundations of health, and our response must be systemic and equally transformative.
Key knowledge gaps: Justice, systems, and opportunity
Although research on climate impacts on health is expanding rapidly, critical knowledge gaps remain. Addressing these gaps, as suggested below, is essential if we are to protect lives, strengthen health systems, and advance justice in a warming world.
Structural inequities and loss
Climate-related health risks are not evenly distributed. Poverty, racism, gender inequality, colonial legacies, and political marginalization shape who is most exposed, who is most vulnerable, and who has the least access to protection [3]. Without confronting these root drivers, climate-health strategies risk reproducing the very inequities they seek to reduce. Equity must be embedded in research design, funding allocation, and implementation research and evaluations.
Infrastructure destruction, livelihood erosion, population displacement, strain on fragile health systems, and profound mental health consequences are unfolding in real time [3]. Yet we still lack robust research methods to understand how systems can withstand cumulative shocks and sustain resilience. This is both a technical and moral challenge - requiring improved methods to measure, anticipate, and respond to compounding risks, while also demanding ethical commitments to justice, accountability, and meaningful support for communities who have contributed least to climate change but bear its greatest burdens.
Systems capacity: Finance, translation, and delivery
Beyond questions of justice, institutional capacity will determine whether solutions can be implemented at scale. For example, climate and health ambitions cannot be realized without fair, predictable, and accessible funding. Without financial integrity, commitments remain aspirational. Furthermore, mechanisms governing how resources are mobilized, who controls allocation decisions, and whether financing mechanisms reach the most affected populations are often not transparent. A clearly outlined health-centred lens integrated into these mechanisms can evaluate not only funding volume, but effectiveness, transparency, and equity. Translating climate data into actionable public health tools also remains underdeveloped. Climate services for health require investment, research and partnerships between weather services and the health sector, with the aim of achieving integrated, climate-informed decision-support systems usable by frontline practitioners and planners [12]. Bridging meteorological expertise, climate modelling tools and public health implementation requires sustained institutional investment and long-term partnerships.
Implementation science is equally critical to closing the persistent ‘know - do’ gap [13]. While evidence on effective interventions for managing heat risks continues to grow, there are still research gaps with regard to efficacy of many climate adaptation and mitigation measures, particularly in health systems. At the same time, we have to think about how to scale promising measures across diverse cultural, geographic, and economic contexts. Acting under uncertainty remains a challenge, in a field where rapid action is needed. Research must therefore generate knowledge about efficacy and at the same time move towards delivery, examining delivery systems, contextual adaptation, workforce capacity, and real-world constraints, particularly in low-resource settings. In transformative research the scientist takes on the role of supporting a transformative change in society, for instance with regard to decreasing inequalities or fostering environmentally sustainable changes. Transformative research can support the closure of the implementation gap by involving stakeholders in the research process. This will only be possible if incentive structures foster transdisciplinary research and reward interdisciplinary collaboration.
Education, knowledge justice, and capacity building
Long-term resilience depends on education at all levels. Climate and health training is increasingly being included in public health education, but other methods are fragmented and often reliant on time-limited, unstable funding [14]. Future professionals working on adaptation require competencies in risk assessment, climate communication, implementation science, systems thinking, sustainable practice, and ethical leadership. Embedding climate literacy not only across health curricula but across primary, secondary and tertiary education more broadly is vital for societal resilience. At the same time, broadening whose knowledge counts is essential. Indigenous and local knowledge systems, community-led research, and lived experience provide insights that are often marginalized in dominant paradigms. Pluralistic approaches strengthen legitimacy, relevance, and the range of viable solutions. This also means diversifying the types of publications to include practice-based scholarship, lessons learned, commentaries on emerging issues, and, perhaps most critically, generative thought leadership, beyond a narrow, formulaic approach to climate-health scholarship. Such contributions can surface implementation insights from the field, elevate underrepresented perspectives, and catalyze new frameworks, research questions, and policy directions that more traditional study designs alone may not capture. Scientific rigor and epistemic humility are mutually reinforcing.
Health co-benefits and the mitigation-adaptation nexus
While much of the climate–health agenda focuses on preventing harm, it is equally important to articulate what can be gained. When individuals seek medical care, they often ask a fundamental question: can this be treated and will I recover? Climate mitigation can be framed in similarly human terms. Cleaner air reduces respiratory and cardiovascular disease. A pollution-free environment mitigates contaminant transfer pathways. Active transport improves physical and mental health. Sustainable food systems have lower emissions while strengthening nutrition security. Climate action, viewed through a health lens, is not a sacrifice that contributes to cost of living but an investment in longer, healthier lives of current and future generations. These co-benefits should be systematically quantified and integrated into economic modelling and policy appraisal to strengthen the case for ambitious decarbonization.
Greater attention must also be paid to the mitigation–adaptation nexus. Integrated strategies, such as urban greening, climate-resilient health facilities powered by renewable energy, and climate-smart food systems, can simultaneously reduce emissions, improve adaptive capacity and health outcomes [15]. Identifying and scaling such ‘triple-win’ solutions is both efficient, because they maximize co-benefits and avoid duplicative investments across sectors, and transformative, because they reshape systems in ways that align climate action with healthier, more resilient communities. Health systems themselves must also confront their environmental footprint, advancing the decarbonization of healthcare delivery while maintaining equitable access and quality of care.
Political economy, trust, and communication
Climate action unfolds within political and economic systems shaped by governance structures, accountability mechanisms, corporate interests, and power asymmetries [15]. Research must therefore examine not only technical interventions but the power structures and decision-making processes that enable or obstruct climate action at political and community levels. Climate–health projections and the economic costs of inaction remain underdeveloped in many regions, particularly in low- and middle-income countries [16]. Robust modelling that integrates health impacts, macroeconomic consequences, and distributional effects can clarify the true cost of delay and inform equitable decision-making. This is particularly important as healthcare systems globally are already facing an unsustainable rise in the cost of healthcare delivery whilst needing to grapple with the expanding healthcare burden associated with climate change. Extreme heat, increased frequency, duration, and intensity of natural hazard disasters, shifting infectious disease patterns, air and water pollution, food insecurity, and population displacement are increasing service demand. Health systems must prepare for chronic, compounding pressures as well as acute shocks [17]. General health system strengthening and maximising efforts towards universal health coverage is one viable way to reach health system resilience.
Climate action also depends on policy makers and communities’ trust in science and its communicators. Even the strongest evidence can fail to catalyse change [18]. Misinformation and disinformation, sorely exacerbated by generative artificial intelligence (AI), threaten effective responses [19]. At the same time, AI systems are increasingly shaping climate–health modelling, policy simulations, and public communication. Research is needed to examine how AI-driven tools influence decision-making, resource allocation, and equity, including risks of algorithmic bias and unequal access across regions. Understanding both the risks and opportunities of AI is essential to ensure that emerging technologies strengthen rather than undermine trust, transparency, and evidence-based climate action. Furthermore, research on science communication, trust-building, and countering false narratives is essential to safeguard democratic decision-making and evidence-based policy. This needs to be a part of designing solutions that are equitable, implementable, and politically informed. Communicating the health impacts of climate change and the health benefits of climate actions is inherently a powerful climate solution. It requires novel research dissemination approaches that go beyond traditional journal publications, such as publicly available dashboards, story maps, podcasts, townhalls, and op-eds in regional newspapers.
Rigour, reproducibility, and ethical responsibility
At a time when scientific authority is frequently contested, methodological rigor, integrity and transparency are essential. As the IPCC’s Seventh Assessment Report (AR7) takes shape, climate-health research can help ensure that global assessments are comprehensive, policy-relevant, and globally representative. High-quality evidence that is transparent about assumptions and uncertainty, attentive to data limitations, and ethically grounded strengthens both scientific progress and public confidence. Research on climate misinformation is also needed to ensure that scientists are better equipped to address future climate communication challenges.
Equity in publishing and knowledge production
Climate change is global, yet academic knowledge production remains uneven. Scholars in high-income countries continue to dominate authorship and agenda-setting, while researchers in low- and middle-income countries face structural barriers to visibility, research funding, and leadership. Addressing this imbalance is both ethically imperative and scientifically necessary. Diverse geographic and cultural perspectives improve research quality, relevance, and legitimacy. Indigenous and community-based insights expand what counts as expertise. The Health section of PLOS Climate is committed to amplifying diverse voices, supporting cross-regional collaboration, and fostering inclusive authorship. The journal and its community of editors will continue to strive to play their part in capacity-building, reducing barriers to publication, and cultivating equitable partnerships that endure beyond individual projects.
Conclusion
As health risks of climate change continue to grow, so too must our collective effort to generate reliable, equitable, and actionable knowledge on climate and health. The challenges are profound, yet within them lies an opportunity to rethink how knowledge is produced, whose voices are elevated, and how science informs decisions that shape lives. Through its Health section, PLOS Climate seeks to nurture a research agenda that is transdisciplinary and interdisciplinary, rigorous, ethically grounded, and oriented toward real-world benefit. We envision a field that enables societies to anticipate risk, reduce inequities, strengthen health systems, and pursue strategies that simultaneously protect the climate and improve public health.
In a complex and uncertain world, constructive, collaborative, and evidence-based climate–health research offers direction. Remaining steadfast in our commitment to mitigation, adaptation, and resilience research cannot be contingent on political cycles or shifting headlines. Instead, it is a professional and moral responsibility shared across disciplines, institutions, and regions. We invite researchers, practitioners, policymakers, and communities worldwide to contribute to this growing body of work that not only measures the costs of inaction, but helps shape pathways toward healthier, more resilient, and more equitable societies.
References
- 1.
United Nations Office for Disaster Risk Reduction (UNDRR). The human cost of disasters: An overview of the last 20 years (2000–2019). Geneva: UNDRR; 2020.
- 2. Zhao Q, Guo Y, Ye T, Gasparrini A, Tong S, Overcenco A, et al. Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study. Lancet Planet Health. 2021;5(7):e415–25. pmid:34245712
- 3.
Intergovernmental Panel on Climate Change (IPCC). Climate Change 2022: Impacts, Adaptation and Vulnerability (WGII). Cambridge: Cambridge University Press; 2022.
- 4. Estallo EL, López MS, Ludueña-Almeida F, Madelón MI, Layún F, Robert MA. Increased risks of mosquito-borne disease emergence in temperate regions of South America. Lancet Region Health Am. 2024.
- 5. Paz S. Climate change: A driver of increasing vector-borne disease transmission in non-endemic areas. PLoS Med. 2024;21(4):e1004382. pmid:38574178
- 6. Romanello M, Napoli C di, Green C, Kennard H, Lampard P, Scamman D, et al. The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-centred response in a world facing irreversible harms. Lancet. 2023;402(10419):2346–94. pmid:37977174
- 7. Kidambi M. A peek into the current climate-health funding landscape. Dimensions. 2024 [cited 2026 Mar 18]. Available from: https://www.dimensions.ai/blog/a-peek-into-the-current-climate-health-funding-landscape
- 8. Whitmee S, Haines A, Beyrer C, Boltz F, Capon AG, de Souza Dias BF, et al. Safeguarding human health in the Anthropocene epoch: report of The Rockefeller Foundation-Lancet Commission on planetary health. Lancet. 2015;386(10007):1973–2028. pmid:26188744
- 9. Gaulton T, Langreiter M, Izon-Cooper L, Cole H, Kovats S, Rother HA, et al. Exploring the interactions between climate change, chemical exposures and public health. Environ Res Health. 2026.
- 10. Song Y, MacEachern L, Doupe MB, Ginsburg L, Chamberlain SA, Cranley L, et al. Influences of post-implementation factors on the sustainability, sustainment, and intra-organizational spread of complex interventions. BMC Health Serv Res. 2022;22(1):666. pmid:35581651
- 11. Penkunas MJ, Dako-Gyeke P, Saravia NG, Mahendradhata Y, Faye A, Rampal S, et al. Unlocking the power of implementation research. BMC Glob Public Health. 2025;3(1):112. pmid:41373057
- 12. WHO-WMO Implementation Plan for Advancing Climate, Environment and Health Science and Services 2023-2033. https://climahealth.info/resource-library/who-wmo-implementation-plan-2023-2033/
- 13.
Peters DH, Tran NT, Adam T. Implementation research in health: A practical guide. Geneva: WHO; 2013. https://iris.who.int/server/api/core/bitstreams/08869e5c-f0e0-49d2-903e-2f85a6336d99/content
- 14. Shaw E, Walpole S, McLean M, Alvarez-Nieto C, Barna S, Bazin K, et al. AMEE Consensus Statement: Planetary health and education for sustainable healthcare. Med Teach. 2021;43(3):272–86. pmid:33602043
- 15. Sovacool BK, Del Rio DF, Zhang W. The political economy of net-zero transitions: Policy drivers, barriers, and justice benefits to decarbonization in eight carbon-neutral countries. J Environ Manage. 2023;347:119154. pmid:37797513
- 16. Carleton T, Jina A, Delgado M, Greenstone M, Houser T, Hsiang S, et al. Valuing the Global Mortality Consequences of Climate Change Accounting for Adaptation Costs and Benefits. Quart J Econ. 2022;137(4):2037–105.
- 17.
World Health Organization. Operational framework for building climate resilient and low carbon health systems. Geneva: WHO; 2021.
- 18. Tal A, Paz S. The political psychology of climate denial. Nat Clim Chang. 2025;16(1):2–4.
- 19. van der Linden S, Leiserowitz A, Rosenthal S, Maibach E. Inoculating the public against misinformation about climate change. Glob Chall. 2017.