Bursting dynamics and network structural changes towards and away from a Pavlovian-conditioned neural network
Fig 6
Persistence of memory following Pavlovian conditioning: D0 = 0.001 μM case.
(A) Raster plots and corresponding SDF profiles depicting the final stage of conditioning (highlighted in the shaded first row) and the subsequent periods after conditioning completion (second to fourth rows). After the conditioning stage, population bursts are self-generated. Note that the SDF profile (blue line) graph shown in the first row has a scale different from those (black lines) of other rows. (B) Scatter plots showcasing the relationship between ∑Win and ∑Wout for all 1,600 excitatory neurons. They are evaluated at the ending time of the corresponding raster plots on their left. The three distinct point colors represent different clusters of excitatory neurons, classified based on their dynamic characteristics (refer to S4 Fig for detailed classification information). Notably, even long after the conclusion of Pavlovian conditioning, the territories occupied by the three neuronal clusters remain quite well-maintained. The self-organized spontaneous burst used for the analysis in Fig 6 is marked with a star symbol in the fourth row. [See S1 Video for the whole process].