System and transcript dynamics of cells infected with severe acute respiratory syndrome virus 2 (SARS-CoV-2)
Fig 1
(a) Mean and standard deviation, along pseudotime, are plotted in log-log scales for each gene. For illustrative purposes, solid lines correspond to the exponential distribution (β = 1 and log(V) = 0), and dashed lines to the Poisson distribution (β = 0.5 and log(V) = –1.7), where log(V) was chosen to be –1.7 for better visualization. The RSI of each gene is color coded. 3207, 4703 and 4433 cells; and 7978, 7567 and 8333 genes were present in each matrix for hBECs, colon and ileum cells, respectively. (b) Distributions of genes in hBECs, as a function of TPT counts, that are to the left of the breakpoint (Poisson, left panel), near the breakpoint (transition, central panel) and to the right of the breakpoint (exponential, right panel), intended to illustrate the transition Poisson to exponential distribution.