Leveraging mathematical modeling framework to guide regimen strategy for phage therapy
Fig 9
In silico cocktail simulations using hypothetical phages.
Comparison of two-phage cocktail treatments under decreased phage binding rate b. (A) Cocktail treatment of Pa+Pb where phage Pa has a low lysis rate (s) and high burst size (h) and Pb inversely has a high lysis rate (potency) and low burst size. (B) Cocktail treatment of Pa+Pb where phage Pa has both high potency and burst size while Pb inversely has low potency and burst size.