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Correction: Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development

  • James J. Collins III,
  • Xiaowen Hou,
  • Elena V. Romanova,
  • Bramwell G. Lambrus,
  • Claire M. Miller,
  • Amir Saberi,
  • Jonathan V. Sweedler,
  • Phillip A. Newmark

Correction: Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development

  • James J. Collins III, 
  • Xiaowen Hou, 
  • Elena V. Romanova, 
  • Bramwell G. Lambrus, 
  • Claire M. Miller, 
  • Amir Saberi, 
  • Jonathan V. Sweedler, 
  • Phillip A. Newmark
PLOS
x

The authors would like to clarify the figure presentation of Figure 7. A corrected legend for Figure 7 is provided here.

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Figure 7. Some prohormone genes are expressed differentially in the CNS of sexual and asexual planarians.

Comparison of the ventral expression of (A) ppl-1 or (B) npy-8 between asexual, immature sexual hatchlings, and mature sexual animals. Whole animal images were obtained using dark-field microscopy. Enlarged views were captured at higher magnification using Rottermann Contrast imaging. Magnified views do not necessarily represent the same focal plane or same individual shown in the whole-animal image. Red dashed boxes indicate the general body regions from which these images were obtained. (C) Dorsal expression of npy-8 in immature sexual hatchlings (left) and mature sexual animals (right). (D) Transparency rendering showing expression of npy-8 in a cell in close proximity to testes lobes. Inset shows higher magnification of npy-8-expressing cell. (E) Northern blot comparing expression of npy-8 in asexual “As,” immature sexual hatchlings “H,” juvenile sexual animals “J,” and mature sexual animals “M.” grb-2 (GB: DN305385) is expressed at similar levels in asexual and sexual animals (J. Stary and P. Newmark, unpublished observations) and is shown as a loading control. Scale bars: (A–C) 300 μm; (D) 10 μm.

https://doi.org/10.1371/journal.pbio.1002234.g001

Reference

  1. 1. Collins JJ III, Hou X, Romanova EV, Lambrus BG, Miller CM, Saberi A, et al. (2010) Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development. PLoS Biol 8(10): e1000509. pmid:20967238