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Potential and limits for rapid genetic adaptation to warming in a Great Barrier Reef coral

April 19, 2018

Potential and limits for rapid genetic adaptation to warming in a Great Barrier Reef coral

Image credit: Mikhail V. Matz and colleagues

PLOS Research News: stay up to date with research from across PLOS

PLOS Research News

04/19/2018

research article

Selection on the regulation of sympathetic nervous activity in humans and chimpanzees

Adrenergic α2C receptor (ADRA2C) is a regulator of the fight-or-flight response, with repression shown to result in relevant physiological and behavioral alterations in mice. In this work, Kang Seon lee and colleagues analyze the genomes, transcriptomes, and epigenomes of a large number of humans and chimpanzees, along with those of other primates, to propose that repression of this gene has been positively selected in the evolution of humans and chimpanzees.

Image credit: Flickr, William Warby, CC-BY

Selection on the regulation of sympathetic nervous activity in humans and chimpanzees

Recently Published Articles

Current Issue

Current Issue March 2018

04/16/2018

research article

Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought

The phytohormone abscisic acid (ABA) is known to mediate drought responses through gene regulation and stomatal closure. Here, Tan, Zhang, Zhou et al show that a HD-ZIP II transcription factor HAT1 negatively regulates ABA-mediated drought responses through suppressing ABA biosynthesis and signaling.

Image credit: Wenrong Tan, Dawei Zhang, Huapeng Zhou and colleagues

Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought

04/16/2018

research article

Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer

In this study, Paulo et al screen 121 prostate cancer patients with strong evidence of a hereditary component for mutations in 94 genes involved in cancer predisposing syndromes. The authors find truncating/functionally deleterious mutations in seven genes and “likely pathogenic” missense variants in four.

Image credit: Paula Paulo and colleagues

Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer

04/05/2018

Review

A genomic overview of the population structure of Salmonella

Alikhan et al discuss the recent proposal to replace serotyping of Salmonella enterica by so-called eBurst groups (eBGs) - based on the alleles of seven housekeeping genes - and the associated problems.

A genomic overview of the population structure of Salmonella

Image credit: Nabil-Fareed Alikhan and colleagues

02/22/2018

perspective

Sex: Not all that it’s cracked up to be?

Eves-van den Akker and Jones comment on work from Blanc-Mathieu et al., who investigate the impact of allopolyploidy on plasticity in the root-knot nematodes Meloidogyne incognita, M. javanica, and M. arenaria.

Sex: Not all that it’s cracked up to be?

Image credit: Sebastian Eves-van den Akker and John T. Jones

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