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acal Is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure

February 24, 2015

acal Is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure

Luis Daniel Ríos-Barrera and colleagues identify and characterize acal as a novel negative dorsal closure regulator. acal represents a new level of JNK regulation. 

Image credit: Luis Daniel Ríos-Barrera and collleagues

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Current Issue February 2015

02/25/2015

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Transhydrogenase Promotes the Robustness and Evolvability of E. coli Deficient in NADPH Production

The structure of biological networks, like traffic systems or the Internet, features few hubs connected by numerous components. Using metabolism as an example, Hsin-Hung Chou and colleagues studied the physiological and evolutionary consequences of genetically perturbed production of a hub metabolite NADPH in E. coli.

Image credit: The Opte Project Wikimedia Commons CC BY

Transhydrogenase Promotes the Robustness and Evolvability of E. coli Deficient in NADPH Production