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MAPK Signaling Pathway Alters Expression of Midgut ALP and ABCC Genes and Causes Resistance to Bacillus thuringiensis Cry1Ac Toxin in Diamondback Moth

April 13, 2015

MAPK Signaling Pathway Alters Expression of Midgut ALP and ABCC Genes and Causes Resistance to Bacillus thuringiensis Cry1Ac Toxin in Diamondback Moth

The diamondback moth was the first insect to evolve field resistance to Bt biopesticides

Image credit: Zhaojiang Guo and colleagues

Recently Published Articles

Current Issue

Current Issue March 2015

04/13/2015

research article

Spastin Binds to Lipid Droplets and Affects Lipid Metabolism

Hereditary spastic paraplegia is a genetically heterogeneous neurological disease characterized by weakness and spasticity of the lower limbs. Chrisovalantis Papadopoulos and colleagues show that the longest spastin form, spastin-M1, harbors a lipid droplet targeting sequence, which allows targeting of the protein to the surface of lipid droplets, the organelles where cells store neutral lipids.

Image credit: Chrisovalantis Papadopoulos and colleagues

Spastin Binds to Lipid Droplets and Affects Lipid Metabolism

04/07/2015

research article

Multi-locus Analysis of Genomic Time Series Data from Experimental Evolution

A growing number of experimental biologists are generating “evolve-and-resequence” (E&R) data in which the genomes of an experimental population are repeatedly sequenced over time. Jonathan Terhorst and colleagues present such a procedure here, and apply it to both simulated and real E&R data.

Multi-locus Analysis of Genomic Time Series Data from Experimental Evolution

Image credit: Leticia Chamorro Flickr CC BY

03/19/2015

Perspective

Morphological Mutations: Lessons from the Cockscomb

Dennis Headon describes the informative collection of morphological mutations published over the past five years by Andersson and colleagues.

Morphological Mutations: Lessons from the Cockscomb

Image credit: Ben Dorshorst and colleagues

03/27/2015

Editorial

PLOS Genetics 2014 Reviewer Thank You

The PLOS Genetics editorial team would like to express our tremendous gratitude to all those individuals who participated in the peer review process this past year.

PLOS Genetics 2014 Reviewer Thank You

Image credit: Center for Scientific Review Wikimedia Commons Public Domain