Advertisement

Recently Published Articles

Current Issue

Current Issue July 2017

08/07/2017

Research article

SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

Chunhong Cheng, Zhijuan Wang and colleagues investigate the regulation of SnRK2 turnover,
and show that SnRK2s are degraded by 26S proteasome and ABA promotes SnRK2.3 degradation. They also show that an F-box protein, AtPP2-B11, which interacts with ASK1 and ASK2, is a component of a SKP1/Cullin/F-box E3 ubiquitin ligase complex.

Image credit: Chunhong Cheng, Zhijuan Wang and colleagues

SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

07/28/2017

research article

Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein

Mutations in BBS6 cause two clinically distinct syndromes, Bardet-Biedl syndrome and McKusick-Kaufman syndrome. Data from this present study finds that BBS6 is actively transported between the cytoplasm and nucleus, and this interaction is disrupted in McKusick-Kaufman syndrome, but not Bardet-Biedl syndrome.  

Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein

Image credit: Charles Anthony Scott and colleagues

07/31/2017

research article

Modular function of long noncoding RNA, COLDAIR, in the vernalization response

The stable repression of a floral repressor, FLC, is a hallmark of the vernalization response in Arabidopsis. This study reveals that the epigenetic repression of FLC during vernalization involves the association of intronic long noncoding RNA COLDAIR with its target chromatin and a chromatin-modifying complex during vernalization.

Modular function of long noncoding RNA, COLDAIR, in the vernalization response

Image credit: Dong-Hwan Kim and colleagues

08/03/2017

research article

Deconstructing isolation-by-distance: The genomic consequences of limited dispersal

Stepfanie M. Aguillon and colleagues investigate the processes that result in spatial genetic structure using the Florida Scrub-Jay. They show how limited dispersal results in close genealogical relatives living closer together geographically, which generates a strong pattern of isolation-by-distance at an extremely small spatial scale, in just a few generations.

Deconstructing isolation-by-distance: The genomic consequences of limited dispersal

Image credit: Stepfanie M. Aguillon and colleagues

07/13/2017

review

Genetic compensation: A phenomenon in search of mechanisms

Mohamed A. El-Brolosy and Didier Y. R. Stainier revisit genetic compensation studies in higher eukaryotes, and outline possible molecular mechanisms of genetic compensation.

Genetic compensation: A phenomenon in search of mechanisms

Image credit: Emma A. Hall, PLOS Genetics, pgen.1003928

Get new content from PLOS Genetics in your inbox

Thank you! You have successfully subscribed to the PLOS Genetics newsletter.

Sorry, an error occurred while sending your subscription. Please try again later.

Try again