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Arabidopsis CaM1 and CaM4 Promote Nitric Oxide Production and Salt Resistance by Inhibiting S-Nitrosoglutathione Reductase via Direct Binding

September 29, 2016

Arabidopsis CaM1 and CaM4 Promote Nitric Oxide Production and Salt Resistance by Inhibiting S-Nitrosoglutathione Reductase via Direct Binding

Salt is a major threat to plant growth and crop productivity. In their study, Shou Zhou and colleagues describe a new molecular function of the Arabidopsis thaliana CaMs in response to salinity, and report that two CaM isoforms AtCaM1 and AtCaM4, which encode the same protein, were stimulated in a salt stress-dependent manner.

Image credit: Robert Nunnally, Flickr, CC BY

09/29/2016

RESEARCH ARTICLE

Drosophila Adaptation to Viral Infection through Defensive Symbiont Evolution

Élio Sucena and colleagues show that a population of Drosophila infected with viruses during several generations adapts to this challenge through turnover in Wolbachia composition. This work demonstrates that the interaction of an animal with a pathogen can shape its associated microbial populations

Image credit: eLife, Flickr, CC BY

Drosophila Adaptation to Viral Infection through Defensive Symbiont Evolution

09/22/2016

RESEARCH ARTICLE

Sex-Specific Selection and Sex-Biased Gene Expression in Humans and Flies

Mark Kirkpatrick and Changde Cheng use genomic data from humans and flies to quantify the relation between ongoing selection pressures and gene expression. A distinctive pattern in both species reveals that many genes are experiencing selection that is currently acting differentially on males and females.

Sex-Specific Selection and Sex-Biased Gene Expression in Humans and Flies

Image credit: balapagos, Flickr, CC BY

09/22/2016

RESEARCH ARTICLE 

The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer

Ngoc-Han Ha and colleagues show that a commonly used model of metastatic breast cancer is capable of identifying genes that play a role in the metastatic progression of ER- breast cancers. They also identify the circadian rhythm gene, Arntl2, as a gene associated with inherited susceptibility for the development of metastatic lesions.

The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer

Image credit: Darryl Leja, NHGRI, Flickr, CC BY