In order to highlight specific topics, PLOS Biology gathers together collections of articles. As with all of our content, all material within collections is published under a Creative Commons Attribution (CC BY) license. 

Under this license, authors agree to make articles legally available for reuse, without permission or fees, for virtually any purpose. Anyone may copy, distribute or reuse these articles, as long as the author and original source are properly cited. Read more about our content license.

Public Engagement in Science

This series aims to investigate whether, and under what conditions, it is possible to engage the public in scientific issues in meaningful ways in decision-making about the innovation pathways of biosciences.

The Promise of Plant Translational Research

The technical advances highlighted in this collection exemplify how basic research discoveries are being translated into methods to develop and improve, both agriculturally and environmentally, important crop traits.

Tenth Anniversary PLOS Biology Collection

In celebration of the Tenth Anniversary of PLOS Biology, this collection showcases ten specially selected PLOS Biology research articles, drawn from a decade of publishing excellent science. The articles, which were chosen by PLOS Biology's Editors and Editorial Board, are representative of the high quality research published in the journal over the last decade. 

The Human Microbiome Project Collection

Funded by the National Institutes of Health Common Fund, the Human Microbiome Project (HMP) was established to provide a comprehensive baseline of the microbial diversity at 18 different human body sites. The Human Microbiome Project Collection encompasses publications from the project.

Oceanic Metagenomics

The J. Craig Venter Institute's Global Ocean Sampling Expedition revealed an enormous amount of unexplored diversity in the world's oceans. This collection includes commentary and analysis highlighting the achievements and challenges of this work.

Challenges Collection

This collection of brief provocative discussion papers, initiated and edited by Simon Levin, aims to highlight fundamental questions in biology that cut across and help unify different biological disciplines.


The Council of Science Editors organized a Global Theme Issue on Poverty and Human Development on October 22, 2007. More than 200 science and health journals, including PLOS Medicine, PLOS Biology, and PLOS Neglected Tropical Diseases, participated by publishing new articles.

Genomics of Emerging Infectious Disease

This collection of essays, perspectives, and reviews from six PLOS Journals provides insights into how genomics can revolutionize our understanding of emerging infectious disease.

Structural Biology and Human Health: Medically Relevant Proteins from the SGC

This collection of articles represents some of the research highlights from the SGC, an international public-private partnership that determines three dimensional structures of medically important proteins from both human and human parasites and places this information into the public domain, free from restrictions on use. 

Epigenetics 2010

This collection reflects a range of model systems and organisms, and offer phenotypic, mechanistic, and chromatin-based insights.

Open Access

In keeping with our primary mission of making the world’s scientific and medical literature a public resource, PLOS periodically publishes articles that explore the issues surrounding open access. Selected articles are featured to highlight key issues relating to open access.

Reporting Guidelines

Highlighting articles including guidance, commentary, and related research on repoarting guidelines. This collection features some of the many resources available to facilitate the rigorous reporting of scientific studies, and to improve the presentation and evaluation of published studies.

Epigenetics 2010

This collection reflects a range of model systems and organisms, and offer phenotypic, mechanistic, and chromatin-based insights.