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Current Issue June 2017

07/20/2017

research article

Advances in using Internet searches to track dengue

As communicable diseases spread in our societies, people frequently turn to the Internet to search for medical information. In recent years, multiple research teams have investigated how to utilize Internet users’ search activity to track infectious diseases around our planet. Yang et al. show that a methodology, originally developed to track flu in the US, can be extended to improve dengue surveillance in multiple countries where dengue has been observed in recent years. 

Image credit: Yang et al.

Advances in using Internet searches to track dengue

07/13/2017

research article

A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis

Mucociliary clearance is the first line of defense of the human pulmonary airways. Mucus transporting debris and pollutants is carried away by the coordinated motion of cilia beating at the surface of the airway epithelium. Bottier et al. present an experimental, mathematical and numerical study aiming to define a global index for assessing the efficiency of this beating.

Image credit: Bottier et al.

A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis

07/17/2017

research article

Atomistic fingerprint of hyaluronan–CD44 binding

In this study, Vuorio et al. show through atomistic molecular dynamics simulations that hyaluronan can bind CD44 with three topographically different binding modes that in unison define an interaction fingerprint. Their insights promote the understanding of the interplay between hyaluronan and HA, thereby fostering development of new drugs or inhibitors to malignancies, such as cancer metastasis.

Atomistic fingerprint of hyaluronan–CD44 binding

Image credit: Vuorio et al.

07/13/2017

research article

Cooperative stochastic binding and unbinding explain synaptic size dynamics and statistics

Synapses are dynamic molecular assemblies whose sizes fluctuate significantly over time-scales of hours and days. In this study, Shomar et al. examine the possibility that the spontaneous microscopic dynamics exhibited by synaptic molecules can explain the macroscopic size fluctuations of individual synapses and the statistical properties of synaptic populations.

Cooperative stochastic binding and unbinding explain synaptic size dynamics and statistics

Image credit: Shomar et al.

07/19/2017

top tweet

Michelle Phillips


There is some really useful advice in here:


Ten Simple Rules for Effective Statistical Practice http://plos.io/2vtEurs Kass et al. #10SimpleRulesTues

Michelle Phillips

Image credit: Twitter

07/19/2017

plos science wednesday

Reddit AMA


PLOS Pathogens author Neus Latorre-Margalef discusses her study showing that one influenza virus may protect against later infections caused by other viruses of different subtypes in mallard ducks.

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Image credit: Ravi Singh/ unsplash.com

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