Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
Emerging single-cell methods for capturing DNA methylation are being developed with the exciting potential to investigate the DNA methylation feature within complex and heterogeneous tissues. In this study, Luo et al. implement a computational pipeline to infer cell-subset specific methylation of embryonic stem cells from single-cell methylome.
Image credit: Luo et al.