Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes
Duwal et al. developed an efficient simulation tool to predict the prophylactic utility of arbitrary dosing regimen. After developing population pharmacokinetic models for dolutegravir (DTG), they set out to predict its prophylactic utility in PrEP, PrEP ‘on demand’ and post-exposure prophylaxis.
Image credit: Duwal et al.