Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach
Fluoroquinolones (FQs) are a class of drug that could help shorten tuberculosis treatment. Pienaar et al. use computer simulations of Mycobacterium tuberculosis infection and FQ treatment within granulomas to predict which FQ is better and why.
Image credit: Pienaar et al.