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History dependence in insect flight decisions during odor tracking

February 12, 2018

History dependence in insect flight decisions during odor tracking

Image credit: Michael Eisen/ Flickr

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Current Issue January 2018

02/13/2018

Research article

Recognition of sites of functional specialisation in all known eukaryotic protein kinase families

Individual kinase families differ extensively in their cognate substrates, binding partners and mode of regulation. The determinants of these specific characteristics are unknown for most kinase families. Using an integrated computational method, tested successfully on known cases, Kalaivani et al. propose a comprehensive list of functionally-specialized sites in all known kinase families.

Image credit: Kalaivani et al.

Recognition of sites of functional specialisation in all known eukaryotic protein kinase families

02/05/2018

research article

A maximum-entropy model for predicting chromatin contacts

Farré and Emberly present a maximum-entropy method able to predict Hi-C contact probabilities from a sequence of binding factors without the need of performing any polymer simulations. In addition, they show the model is capable of solving the inverse problem, namely predicting the underlying sequence of binding factors from a set of observed contact probabilities.

A maximum-entropy model for predicting chromatin contacts

Image credit: Farré, Emberly.

09/28/2007

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Synthetic 'dead leaves'

Synthetic 'dead leaves'

Image credit: David Corney and R. Beau Lotto (http://www.lottolab.org)

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