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Border Security Fencing: Impact on Wildlife

June 22, 2016

Border Security Fencing: Impact on Wildlife

While cooperation across national boundaries has emerged as a key concept in wildlife conservation, this Perspective by John Linnell and colleagues reveals that the dramatic increase in the extent of security fencing along international borders has far-reaching consequences for this approach.

Image credit: Freedom House

Open Highlights: Highlighting Open Access research from PLOS and beyond

Biologue

06/22/2016

community page

Interactive Data Visualization to Improve Transparency

This article by Tracey Weissgerber, Vesna Garovic, Natasa Milic and co-authors examines the potential for interactive graphics to transform scientific papers from static publications into interactive datasets and provides a web-based tool for creating interactive line graphs.

Image credit: 10.1371/journal.pbio.1002484.g001

Interactive Data Visualization to Improve Transparency

Recently Published Articles

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Current Issue May 2016

06/09/2016

research article

Color of Light Regulates Sleep and Arousal via Melanopsin

Light can produce either sleep or arousal in mice. This study by Violetta Pilorz, Russell Foster, Stuart Peirson and co-authors reveals that these opposing effects depend upon the wavelength of light and appear to involve separate pathways, both modulated by the photopigment melanopsin.

Image credit: Flickr user, pilottage

Color of Light Regulates Sleep and Arousal via Melanopsin

06/14/2016

Primer

Authentication: A Standard Problem or a Problem of Standards?

A major contributor to the lack of reproducibility in preclinical research is insufficient quality assurance of reagents used. This article by Amanda Capes-Davis and Richard Neve examines the problems surrounding the authentication of cell lines and discusses potential solutions. Read the related Perspective.

Image credit: 10.1371/journal.pbio.1002477.g001

Authentication: A Standard Problem or a Problem of Standards?

06/14/2016

Perspective

Standards for Cell Line Authentication and Beyond

While definitive methods for human cell line authentication have been compiled in a documentary standard, this Perspective by Jamie Almeida, Kenneth Cole and Anne Plant maintains that more research is required to provide similar vetting of methods for non-human cell lines. Read the related Primer.

Standards for Cell Line Authentication and Beyond

Image credit: Flickr user, niceness

06/01/2016

research article

How Streptomyces Evolved to Decompose Cellulose

Cellulose deconstruction helps shape the global carbon cycle; this study by Adam Book, Gina Lewin, Cameron Currie and colleagues shows that high cellulolytic ability evolved in select lineages of the bacterial genus Streptomyces through key changes in gene content and transcriptional regulation.

How Streptomyces Evolved to Decompose Cellulose

Image credit: Don Parsons

06/09/2016

research article

Gilgamesh and Smoothened in Hedgehog Signaling

A study of both fruit flies and vertebrate cells, by Shuangxi Li, Shuang Li, Jin Jiang and co-workers, shows that the plasma membrane-associated kinase Gish/CK1γ promotes transduction of the Hedgehog signal by phosphorylating Smoothened.

Gilgamesh and Smoothened in Hedgehog Signaling

Image credit: 10.1371/journal.pbio.1002481

06/09/2016

research article

How Streptomycin Gets into Bacteria

The antibiotic streptomycin binds to a specific site on the bacterial channel MscL, opens the pore, and appears to pass through it to access the cytoplasm of the cell.

How Streptomycin Gets into Bacteria

Image credit: 10.1371/journal.pbio.1002473

06/09/2016

research article

Ribosome Assembly: Removing the Assemblers

ATP hydrolysis by the DEAD-box protein Rok1 helps release assembly factor Rrp5 from pre-40S subunits during ribosomal biogenesis.

Ribosome Assembly: Removing the Assemblers

Image credit: 10.1371/journal.pbio.1002480

06/09/2016

research article

Connecting Membrane Tension to Actin Assembly

A mechanosensory cascade involving PLD2 and mTORC2 coordinates physical forces and cytoskeletal rearrangements to allow neutrophil migration.

Connecting Membrane Tension to Actin Assembly

Image credit: 10.1371/journal.pbio.1002474

06/16/2016

plos biologue

PLOS Biology at ASM Microbe 2016

To mark the ASM Microbe conference, Lauren Richardson looks at some of the fantastic microbiology we've published this year.

PLOS Biology at ASM Microbe 2016

Image credit: Johan Ruhe