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Drug Hits Target During Translation

March 21, 2017

Drug Hits Target During Translation

Nathanael Lintner, Robert Dullea, Jamie Cate and co-workers reveal that a small molecule can inhibit synthesis of the clinically significant target PCSK9 by selectively stalling the human ribosome, dependent on the sequence of the nascent chain inside the ribosome exit tunnel.

Image credit: pbio.1000581

PLOS Research News: stay up-to-date with research published in PLOS

PLOS Research News

03/21/2017

community page

Liquid-Handling Lego Robots

Lukas Gerber, Ingmar Riedel-Kruse and colleagues show that liquid-handling robots based on Lego Mindstorms can handle sub-microliter to milliliter liquid volumes and support K-12 STEM education and research; instructions for building and low-cost experiments are provided.

Image credit: pbio.2001413

Liquid-Handling Lego Robots

Recently Published Articles

Current Issue

Current Issue February 2017

03/22/2017

community page

Crowdsourcing Ideas for Conservation: Tigers

Özgün Emre Can, Neil D’Cruze, Margaret Balaskas and David Macdonald reveal how crowdsourcing can encourage innovation in the fields of ecology, wildlife conservation and animal protection by contributing to the development of new tools and approaches.

Image credit: Özgün Emre Can

Crowdsourcing Ideas for Conservation: Tigers

03/20/2017

Perspective

Walking and Talking (and Eating!) the Tree of Life

This Perspective article by Cissy Ballen and Harry Greene finds that outdated approaches to teaching the tree of life are widespread, and highlights the need to promote a phylogenetic approach that focuses on common ancestry and derived functional traits.

Image credit: pbio.2001630

Walking and Talking (and Eating!) the Tree of Life

03/21/2017

community page

Teaching Societal Impacts of Science

This Community Page article by Kenneth Keiler, Sarah Ades and co-authors describes an innovative undergraduate course that develops scientific and ethical decision-making skills by integrating research with the broader impacts of science on society.

Teaching Societal Impacts of Science

Image credit: Flickr user: Luke Jones

03/20/2017

editorial

PLOS Biology Says "Thank You!"

A heartfelt "thank you" from the PLOS Biology editorial team to the 286 academic and guest editors and 1,285 reviewers who helped us by handling and assessing articles during the past year.

PLOS Biology Says "Thank You!"

Image credit: Flickr user: Tall Chris

03/14/2017

research article

Red Algae from 1,600,000,000 Years Ago

1.6 billion-year-old fossils from central India, described by Stefan Bengtson, Therese Sallstedt, Veneta Belivanova and Martin Whitehouse, spark new ideas about the early evolution of multicellular red algae, pushing back their emergence by 400 million years.

Red Algae from 1,600,000,000 Years Ago

Image credit: Stefan Bengtson

03/14/2017

research article

Antibiotics Disrupt Honeybee Gut Microbiota

Antibiotic exposure severely alters the gut microbial community structure of honeybees, increasing susceptibility to pathogen infection and reducing survival.

Antibiotics Disrupt Honeybee Gut Microbiota

Image credit: Flickr user: Paul Rollings

03/16/2017

research matters

Life is 3D and Begins with Molecules

Structural biology seen through the career of one long-time researcher, during which time the freely accessible public collection of structures grew from less than 100 to more than 126,000.

Life is 3D and Begins with Molecules

Image credit: pbio.1002140

03/16/2017

research matters

Genome Editing: Bioethics Shows the Way

Bioethics advances innovative research that raises ethical questions, but also hopes to provide solutions to some of our world’s greatest challenges.

Genome Editing: Bioethics Shows the Way

Image credit: Flickr user Caroline Davis2010

03/04/2017

plos biologue

Hooray for Open Data Day!

What if, just for one day, we all took some time to focus and think about Open Data? Emma Ganley discusses why March 4th, 2017 was a day to do just that—to promote awareness and use of Open Data.

Hooray for Open Data Day!

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