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Selection Constrains Genetic Diversity across Species

April 10, 2015

Selection Constrains Genetic Diversity across Species

Russell Corbett-Detig, Daniel Hartl and Timothy Sackton use whole-genome genetic variation data from 40 species to explain why levels of neutral diversity do not scale with population size. Read the accompanying Synopsis.

Image credit: Flickr users Liz West, Ronnie Macdonald, Nikita, Mark Jordahl

04/17/2015

research article

Color Entrains the Circadian Clock

Environmental measurements and physiological recordings, by Lauren Walmsley, Robert Lucas, Timothy Brown and co-authors, reveal that mice not only use changes in the intensity of sunlight to entrain their circadian clock, but also employ blue–yellow color discrimination to detect spectral changes associated with dawn and dusk.

Image credit: Flickr user 白士 李

Color Entrains the Circadian Clock

Recently Published Articles

Current Issue

Current Issue March 2015

04/16/2015

research article and primer

Fly Sex Chromosomes Are Highly Dynamic

Analysis of the genomes of 37 fly species from 22 families, conducted by Beatriz Vicoso and Doris Bachtrog, shows that superficially similar karyotypes conceal the true extent of sex chromosome variation and that sex chromosome transitions are in fact frequent in flies. Read the Primer by Kevin Wei and Daniel Barbash.

Image credit: Flickr user Marcelo César Augusto Romeo

Fly Sex Chromosomes Are Highly Dynamic

04/15/2015

Essay

Stopping Marine Invaders

Classifying the impact of non-indigenous species presents special problems in marine environments. This Essay by Henn Ojaveer and co-authors presents a framework that focuses on values and emphasizes precaution in managing the data limitations and uncertainties that are found in the marine context.

Image credit: public domain

Stopping Marine Invaders

04/14/2015

research article and synopsis

How Salmonella Survives Acid Attack

Smarajit Chakraborty, Hideaki Mizusaki and Linda Kenney find that, rather than using the cadaverine operon to combat the acid conditions of the macrophage vacuole, Salmonella allows its cytoplasm to become acidified, which in turn drives secretion of effectors into the host cell. Read the Synopsis.

How Salmonella Survives Acid Attack

Image credit: doi:10.1371/journal.pbio.1002116.g009

04/13/2015

research article

Bundling Microtubules during Cytokinesis

Cell division depends on the antiparallel bundling of microtubules by a motor complex called centralspindlin. This study by Tim Davies, Noriyuki Kodera, Masanori Mishima and co-authors reveals how the centralspindlin non-motor subunit CYK4 reconfigures the motor domains of the kinesin subunit MKLP1 to help it carry out this role.

Bundling Microtubules during Cytokinesis

Image credit: doi:10.1371/journal.pbio.1002121.g008

04/10/2015

research article

Reassembling the Primary Cilium

Boyan Zhang, Chuanmao Zhang and co-workers show how the asymmetric assembly of a new primary cilium in one of two daughter cells after mitosis is regulated by a cascade involving GSK3β, Dzip1, and Rab8.

Reassembling the Primary Cilium

Image credit: doi:10.1371/journal.pbio.1002129.g001

04/09/2015

education

The Virtual Cell Animation Collection

Freely available multimedia materials designed to help molecular and cellular biology students conceptualize the dynamic nature of cells.

The Virtual Cell Animation Collection

Image credit: doi:10.1371/journal.pbio.1002118.g001

04/02/2015

Research article

Spontaneous Polarization of Cdc42

Active and inactive forms of the small GTPase Cdc42 have different rates of lateral diffusion, enabling spontaneous determination of cell polarity.

Spontaneous Polarization of Cdc42

Image credit: doi:10.1371/journal.pbio.1002097.g005