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How Many Human and Bacterial Cells in the Body?

August 19, 2016

How Many Human and Bacterial Cells in the Body?

Thoroughly revised estimates by Ron Sender, Shai Fuchs and Ron Milo show that the typical adult human body consists of about 30 trillion human cells and about 38 trillion bacteria

Image credit: pbio.1002533

Open Highlights: Highlighting Open Access research from PLOS and beyond

Biologue

08/15/2016

Research Article

How Sec4p Regulates Compensatory Endocytosis

Maintaining a constant cell membrane area depends on a balance between endocytosis and exocytosis. This study by Jesper Johansen, Gabriel Alfaro and Christopher Beh shows that the yeast Rab GTPase Sec4p, a well-established regulator of polarized exocytosis, induces compensatory endocytosis by promoting cortical actin polymerization.

Image credit: pbio.1002534

How Sec4p Regulates Compensatory Endocytosis

Recently Published Articles

Current Issue

Current Issue July 2016

08/15/2016

 Primer

Alerting or Somnogenic Light: Pick Your Color

Recent research has revealed further complexity in how the color spectrum of light influences sleep and alertness. This Primer by Patrice Bourgin, Jeffrey Hubbard examines the risks and benefits that light poses to animals, the implications for humans, and the design of the lighting environment. Read the related Research Article.

Image credit: Flickr user Pilottage

Alerting or Somnogenic Light: Pick Your Color

08/10/2016

Research Article

Cortical Frontal Eye Fields Control Microsaccades

Our eyes are constantly in motion. This study by Tyler Peel, Brian Corneil and colleagues shows that the frontal eye fields (an area of the frontal cortex) contribute to the strategic deployment of microsaccades, which aid vision by precisely translating retinal images by a few photoreceptors.

Image credit: Flickr user Jean-Manuel Fernandez

Cortical Frontal Eye Fields Control Microsaccades

08/09/2016

 Research Article

Natural Constraints to Species Diversification

A meta-analysis by Eric Lewitus and Hélène Morlon of 214 family-level vertebrate trees containing more than 12,000 species and spanning 500 million years of evolution reveals general patterns of species diversification and the constraints acting on them.

Natural Constraints to Species Diversification

Image credit: pbio.1002532

08/11/2016

 Research Article

Mending Broken Hearts

Qiulun Lu, Yufeng Yao, Qing Kenneth Wang and co-workers find that treatment with the angiogenic factor AGGF1 dramatically improves survival and cardiac function in mouse models of coronary artery disease and myocardial infarction by activating autophagy and angiogenesis.

Mending Broken Hearts

Image credit: pbio.1002529

08/08/2016

Research Article

How Natural Killer Cells Choose Diversity

Jacquelyn Freund, Taku Kambayashi and co-authors reveal that during the development of natural killer (NK) cells, activating receptor signaling drives the acquisition of inhibitory receptors during development, leading to the creation of a diverse pool of ligand-specific NK cells.

How Natural Killer Cells Choose Diversity

Image credit: pbio.1002526

08/10/2016

Community Page

Modelling Dynamic Biological Pathways

Presenting a biologist-friendly method for compiling detailed graphical models of biological pathways from the literature, including their use in dynamic simulations. See the video.

Modelling Dynamic Biological Pathways

Image credit: pbio.1002530

08/03/2016

research article

Untangling a Comprehensive Ecological Network

A network of all known interactions between species shows a clear pattern of organization that reflects evolutionary and ecological constraints operating in this entangled bank of species.

Untangling a Comprehensive Ecological Network

08/05/2016

 Research Article

How Human Brains Replay the Past

Study of the mental replay of audio and video clips reveals that the phase of an 8-Hz oscillation carries a temporal code of individual visual and auditory memories.

How Human Brains Replay the Past

Image credit: Thomas Raatz

08/12/2016

PLos biologue

Black Sigatoka and Bananas

Gert Kema describes the unfortunate consequences of deriving almost all bananas from a single global clone and discusses his PLOS Genetics paper about the Black Sigatoka fungus.

Black Sigatoka and Bananas

Image credit: GHJ Kema