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Slam Protein Localizes its own mRNA

December 4, 2017

Slam Protein Localizes its own mRNA

Shuling Yan, Jörg Großhans and co-workers find that during the cellularization process in Drosophila, slam mRNA and Slam protein form a complex and colocalize at the basal domain of the developing epithelium; this interaction enables the spatiotemporal control of translation.

Image credit: Dr. Shuling Yan

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PLOS Research News

12/07/2017

research article

The Circadian Clock, the Cell Cycle and Cancer

A combined computational and experimental study by Rukeia El-Athman, Nikolai Genov, Jeannine Mazuch, Angela Relógio and colleagues highlights the role of the circadian clock as a tumour suppressor, and identifies Ink4a/Arf as a mediator of RAS-induced clock dysregulation that affects cell cycle decisions.

Image credit: Pixabay

The Circadian Clock, the Cell Cycle and Cancer

Recently Published Articles

Current Issue

Current Issue November 2017

12/04/2017

research article

Task-Relevance and Sensory Prediction

As their environment changes, animals need to learn and continuously update predictions about their current context to optimize behavior. Model-based analysis of neural data by Ryszard Auksztulewicz, Karl Friston and Anna Nobre revealed correlates of predictions and prediction errors; both of these were modulated by their relevance to the task in hand.

Image credit: Pixabay

Task-Relevance and Sensory Prediction

11/28/2017

research article

Systemic Resilience Of The Great Barrier Reef

By modelling regional connectivity patterns, this study by Karlo Hock, Peter Mumby and colleagues reveals that Australia’s Great Barrier Reef has a network of around 100 coral reefs that are ideally suited to promoting the recovery of the ecosystem after major coral bleaching events.

Image credit: Peter J Mumby

Systemic Resilience Of The Great Barrier Reef

11/27/2017

research article

Antibiotic Crosstalk during Co-Infections

Lauren Radlinski, Brian Conlon and co-authors show that exoproducts secreted by the bacterium Pseudomonas aeruginosa alter the susceptibility of Staphylococcus aureus to multiple classes of antibiotics and impact the therapeutic outcome during the treatment of co-infections.

Antibiotic Crosstalk during Co-Infections

Image credit: Flickr user: NIAID

11/29/2017

research article

Adolescent Stress, trkB and Depression

A mouse study by Elizabeth Barfield, Shannon Gourley and co-workers shows that exposure to the stress hormone corticosterone during adolescence impairs decision-making behavior in adulthood, which is related to long-lasting changes in neurotrophin signaling. Decision making can be normalized by treatment with a drug that stimulates the neurotrophin trkB receptor.

Adolescent Stress, trkB and Depression

Image credit: Flickr user: Ninian Reid

11/30/2017

community page

Sonic Kayaks: Environmental Data & Augmented Reality

In this Community Page article by Amber Griffiths, Kirsty Kemp, Kaffe Matthews, Joanne Garrett & David Griffiths, kayaks rigged with underwater sensors allow paddlers to hear sonifications of real-time water temperature and underwater sounds, generating live music from the marine world while collecting valuable environmental research data.

Sonic Kayaks: Environmental Data & Augmented Reality

Image credit: Pixabay

11/30/2017

research article

Perceptual Integration in Noisy Scenes

A rapid reverse hierarchical activation along the dorsal visual pathway supports a global-to-local processing cascade that helps resolve ambiguities in noisy environments.

Perceptual Integration in Noisy Scenes

Image credit: pbio.2003646

11/30/2017

methods and resources

CRISPR-Cas9 versus RNAi

A systematic comparison of CRISPR-Cas9 and RNA interference (RNAi) reveals that while on-target efficacies are comparable, CRISPR has far fewer off-target effects than RNAi.

CRISPR-Cas9 versus RNAi

Image credit: RCSB PDB

11/21/2017

methods and resources

From Tissue to DNA/RNA in 30 Seconds

A simple nucleic acid extraction method makes DNA amplification applications quicker, cheaper, and more accessible to researchers and the broader community.

From Tissue to DNA/RNA in 30 Seconds

Image credit: pbio.2003916

11/21/2017

perspective

The Sugar Industry and Health

This Perspective uses internal sugar industry documents to explore what the industry knows about sugar, the microbiome, and cancer biomarkers… and when they knew it.

The Sugar Industry and Health

Image credit: Flickr user rudeworks

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