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From Tissue to DNA/RNA in 30 Seconds

November 21, 2017

From Tissue to DNA/RNA in 30 Seconds

Yiping Zou, Michael Glenn Mason, Jose Ramon Botella and colleagues describe a simple nucleic acid extraction method that will help to streamline DNA amplification-based applications, making them more accessible and affordable to researchers and the broader community.

Image credit: pbio.2003916

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PLOS Research News

11/21/2017

perspective

The Sugar Industry and Health

Cristin Kearns, Dorie Apollonio and Stanton Glantz use internal sugar industry documents to explore what the industry knows about sugar, the microbiome, and cancer biomarkers… and when they knew it.

Image credit: Flickr user rudeworks

The Sugar Industry and Health

Recently Published Articles

Current Issue

Current Issue October 2017

11/17/2017

research article

Genetic Basis of Fungal Secondary Metabolite Diversity

Genome sequence analysis by Abigail Lind, Antonis Rokas and colleagues demonstrates that strains of a single fungal species, Aspergillus fumigatus, differ extensively in their secondary metabolism pathways, revealing how fungal chemodiversity is generated at the level of the genome.

Image credit: ppat.1002372

Genetic Basis of Fungal Secondary Metabolite Diversity

11/21/2017

community page

Mutualism in Museums

Natural history museums can uniquely engage students in hands-on learning. This Community Page article by Anna Hiller, Carla Cicero, Eileen Lacey and co-authors lays out the design of a museum-based program and its benefits to both undergraduate students and collections.

Image credit: pbio.2003318

Mutualism in Museums

11/14/2017

research article

Pioneers or Settlers? A Prion Makes the Switch

Gregory Newby and the late Susan Lindquist reveal that an epigenetic prion switch in yeast specializes the cells either into “pioneers” that readily disperse in water and disfavor inbreeding, or into “settlers” that have enhanced resilience and adhesion.

Pioneers or Settlers? A Prion Makes the Switch

Image credit: pbio.2003476

11/14/2017

research article

Making Economic Decisions

How does attention shape the way that we perceive value and make decisions? Habiba Azab and Benjamin Hayden show that neuronal encoding of offer value in dorsal anterior cingulate cortex partially depends on the upcoming decision; this dependence increases as offers are compared, reflecting the evolving economic decision.

Making Economic Decisions

Image credit: Flickr user: Images Money

11/16/2017

essay

A Forgotten 1960s Experiment in Biological Preprints

In 1961, the NIH began a little-known experiment in biological preprints which was killed off by pressure from publishers in 1967. This article by Matthew Cobb reveals this hidden history and draws lessons.

A Forgotten 1960s Experiment in Biological Preprints

Image credit: pbio.2003995

11/16/2017

perspective

Gene Drive for Conservation: Use with Caution!

The promise and potential pitfalls of the use of gene drive technologies in conservation necessitate open, international discussions.

Gene Drive for Conservation: Use with Caution!

Image credit: Maungatautari Ecological Island Trust

11/08/2017

research article

Compensation in the Aging Thymus

Aging-induced thymic atrophy involves making more thymic regulatory T cells in an attempt to compensate for defects in thymocyte negative selection.

Compensation in the Aging Thymus

Image credit: Flickr user: NIAID

11/06/2017

research article

Glutamine, DNA Damage and Cancer

Examination of the crosstalk between glutamine metabolism and DNA repair pathways reveals how glutamine deficiency promotes genomic instability and modulates the response to therapy in cancer.

Glutamine, DNA Damage and Cancer

Image credit: PubChem

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