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The Functional Connectome of Speech Control

July 23, 2015

The Functional Connectome of Speech Control

This study by Stefan Fuertinger, Barry Horwitz and Kristina Simonyan uses graph theory to analyze functional MRI data recorded from speakers as they produce single syllables or whole sentences, revealing the complexity of the brain network machinery that controls speech and language.

Image credit: Stefan Fuertinger, Kristina Simonyan

07/23/2015

Community Page

Biodiversity E-Infrastructures for Megadiverse Countries

This Community Page, from Dora Canhos, Mariane Sousa-Baena, Townsend Peterson and colleagues, calls for new governance and funding models to ensure the sustainability of national e-infrastructures—important for global systems and crucial for local education, research, and policy

Image credit: Flickr user Gilad Rom

Biodiversity E-Infrastructures for Megadiverse Countries

Recently Published Articles

Current Issue

Current Issue June 2015

07/23/2015

essay

Diffusion MRI: What Water Tells Us about Biological Tissues

This Essay by Denis Le Bihan and Mami Iima looks at the history and future potential of diffusion magnetic resonance imaging (MRI), a powerful imaging concept that gives non-invasive insights into brain architecture and function—whether normal or diseased.

Image credit: 10.1371/journal.pbio.1002203.g002

Diffusion MRI: What Water Tells Us about Biological Tissues

07/21/2015

Research Article and synopsis

Parasite Uncovers New Modulator of STAT1

Exploitation of the parasite Toxoplasma gondii allows Daniel Beiting, David Roos, Sara Cherry and co-workers to identify the host orphan nuclear hormone receptor TLX as a key enhancer of STAT1-dependent immune signaling and host defense. Read the Synopsis.

Image credit: 10.1371/image.pbio.v10.i12

Parasite Uncovers New Modulator of STAT1

07/15/2015

Research Article

Photoreceptor Degeneration in Mitochondrial Mutants

Some mitochondrial disorders cause blindness through increased oxidative stress. Manish Jaiswal, Hugo Bellen and co-authors show that in other such disorders, light-activated photoreceptors degenerate because of the shortfall in mitochondrial energy production.

Photoreceptor Degeneration in Mitochondrial Mutants

Image credit: Manish Jaiswal

07/14/2015

Research Article

Which Kids Will Struggle to Read?

Travis White-Schwoch, Nina Kraus and co-authors reveal that the neural coding of consonants in noise predicts early literacy skills in pre-reading children, providing a biological marker that may help to target early intervention to those most in need.

Which Kids Will Struggle to Read?

Image credit: Flickr user Germán Poo-Caamaño

07/14/2015

Research Article

The Myriad Viruses of Drosophila melanogaster

Claire Webster, Darren Obbard and co-workers use sequencing of metagenomic RNA and small RNA to identify more than 20 new viruses associated with the fruit fly Drosophila melanogaster; large-scale surveys show that many are common in the lab and in the field.

The Myriad Viruses of Drosophila melanogaster

Image credit: Biodiversity Heritage Library

07/16/2015

Research Article

Lactate Controls T Cell Activity

High levels of lactate that accumulate in chronic inflammatory sites can trigger unfavorable responses in infiltrating T cells; reducing sensitivity to lactate might help ameliorate chronic inflammatory disorders.

Lactate Controls T Cell Activity

Image credit: NIAID

07/09/2015

research article and synopsis

Cannabis: Separating "Good" and "Bad" Effects

Receptor subtypes interact to form heterodimers that mediate the cognitive deficits—but not the analgesic effects—induced by tetrahydrocannabinol. Read the Synopsis.

Cannabis: Separating "Good" and "Bad" Effects

Image credit: Biodiversity Heritage Library

07/09/2015

research article

Biofilm Formation - a Response to Antibiotic Warfare

Mixing natural isolates of the pathogenic bacterium Pseudomonas aeruginosa reveals that the formation of biofilm is a response to antibiotic stress from competing genotypes.

Biofilm Formation - a Response to Antibiotic Warfare

Image credit: Nuno Miguel Oliveira