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Spatially Regulated miRNA Degradation

February 23, 2017

Spatially Regulated miRNA Degradation

A genetic and biochemical study in Arabidopsis thaliana by Yu Yu, Lijuan Ji, Brandon Le, Xuemei Chen and co-authors establishes a molecular framework for microRNA degradation and provides an example of specificity determination involving an ARGONAUTE protein.

Image credit: pbio.2001272

PLOS Research News: stay up-to-date with research published in PLOS

PLOS Research News

02/24/2017

research article

Is it Worth the Effort?

Model-based fMRI in humans by Trevor Chong, Matthew Apps, Masud Husain and colleagues shows that cognitive and physical motivation are underpinned by overlapping neural substrates, but the amygdala plays a unique role in valuation of cognitive effort.

Image credit: pbio.1002598

Is it Worth the Effort?

Recently Published Articles

Current Issue

Current Issue January 2017

02/21/2017

open highlight

Putting Placebos to the Test

Medics have long recognised the curious power of the placebo. This Open Highlight by Liza Gross explores recent research into its biological basis and the complex ethical and practical issues that surround this phenomenon.

Image credit: US National Library of Medicine

Putting Placebos to the Test

02/22/2017

primer

Explaining the "Paradox of Stasis"

This Primer by Loeske Kruuk examines a new study that suggests an intriguing explanation for the counterintuitive evolutionary dynamics of body size in a wild population of snow voles. Read the accompanying Research Article.

Image credit: Timothée Bonnet

Explaining the "Paradox of Stasis"

02/16/2017

research article

ENS Constrains Intestinal Microbiota

Annah Rolig, Judith Eisen, Karen Guillemin and colleagues study zebrafish lacking an enteric nervous system, revealing a striking role for these neurons in maintaining a balanced intestinal microbial community and preventing intestinal inflammation.

ENS Constrains Intestinal Microbiota

Image credit: pbio.2000689

02/16/2017

Research article

Narciclasine Reduces Diet-Induced Obesity

Sofi Julien, Sun-Yee Kim, Feng Xu and co-workers show that the natural compound narciclasine attenuates diet-induced obesity in mice by promoting energy expenditure; it also induces a number of beneficial metabolic effects and activates AMPK signaling in skeletal muscle.

Narciclasine Reduces Diet-Induced Obesity

Image credit: pbio.1002597

02/15/2017

essay

Ecological Networks Can Inform Transposon Transfers

This Essay by Samuel Venner, Dominique Pontier and co-authors proposes network theory as a robust conceptual framework to delineate how complex interactions between diverse organisms may synergize to promote horizontal transfer of transposable elements.

Ecological Networks Can Inform Transposon Transfers

Image credit: pbio.2001536

02/16/2017

research article

Serotonin in Reward and Effort Learning

A study using a commonly prescribed antidepressant reveals that raised serotonin levels can increase neural and behavioral measures of learning about rewards and effort in healthy humans.

Serotonin in Reward and Effort Learning

Image credit: pbio.2000756

02/15/2017

perspective

Harnessing the Creativity of the Scientific Crowd

The potential of open innovation to improve drug discovery can only be realized by establishing reliable frameworks to convert the crowd output into actionable plans.

Harnessing the Creativity of the Scientific Crowd

Image credit: pbio.2001387

12/22/2016

PLOS Biologue

Celldance Videos at ASCB 2016

PLOS sponsored the production of the Celldance videos at ASCB 2016. Ines Alvarez-Garcia discusses these visually astounding works and discovers the motivation behind them


Celldance Videos at ASCB 2016

Image credit: Renaud Chabrier

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