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Malaria in a Changing Climate

October 17, 2017

Malaria in a Changing Climate

A comprehensive study by Lillian Shapiro, Shelley Whitehead and Matthew Thomas of the life history traits of the mosquito Anopheles stephensi and the human malaria parasite Plasmodium falciparum under a range of temperatures reveals new insights into the transmission dynamics of this important disease.

Image credit: Centers for Disease Control and Prevention

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PLOS Research News

10/18/2017

research article

Replicate or Lie Low? How HIV Makes its Choice

Brandon Razooky, Michael Simpson, Leor Weinberger and co-authors use a combination of computational modeling and experiment to explain how HIV's gene regulatory circuit architecture is optimized to ensure a probabilistic decision between alternate fates.

Image credit: Flickr user NIAID

Replicate or Lie Low? How HIV Makes its Choice

Recently Published Articles

Current Issue

Current Issue September 2017

10/19/2017

methods and resources

Ectomap - a Molecular Atlas of the Frog Ectoderm

Transcriptomics of microdissected developing frog ectoderm, by Jean-Louis Plouhinec, Sofía Medina-Ruiz, Anne Monsoro-Burq and co-workers, yields positional information and gene co-expression patterns, allowing computational retrieval of gene expression relationships relevant to development, cancer, evo-devo and stem cell biology. 

Image credit: pbio.2004045

Ectomap - a Molecular Atlas of the Frog Ectoderm

10/19/2017

community page

Make Yourself an Ethoscope... from Card, LEGO or 3D-Print

This Community Page article by Quentin Geissmann, Giorgio Gilestro and colleagues presents a DIY approach to building ethoscope machines able to analyse behaviour of fruit flies in a high-throughput fashion. Ethoscopes are powerful yet accessible, and can be used by scientists and enthusiasts alike.

Image credit: Giorgio Gilestro

Make Yourself an Ethoscope... from Card, LEGO or 3D-Print

10/12/2017

research article

The Sea Cucumber Genome

The high-quality genome sequence of the sea cucumber Apostichopus japonicus by Xiaojun Zhang, Jianhai Xiang and colleagues provides a resource for research on echinoderm and deuterostome biology, comparative genomics and commercial breeding.

The Sea Cucumber Genome

Image credit: Qiang Xu

10/04/2017

research article

Female Body Growth Controlled by Sex of Specific Neurons

Annick Sawala and Alex Gould show that female fruit flies grow faster than males during larval development and that this depends upon expression of the sex determination gene Sex-lethal in two specific subsets of neurons in the brain.

Female Body Growth Controlled by Sex of Specific Neurons

Image credit: Annick Sawala & Alex Gould

09/29/2017

research article

Intron Retention Regulates Translation during Hypoxia

Transcriptomic analysis of head and neck cancer cells by Lauren Brady, Constantinos Koumenis and co-authors reveals alternative splicing of EIF2B5 as a previously uncharacterized mechanism of translational control under conditions of hypoxia.

Intron Retention Regulates Translation during Hypoxia

Image credit: pbio.2002623

09/27/2017

research article

Segmentation: from Short-Germ to Long-Germ

Kinematic expression waves of a pair-rule gene are crucial for segment patterning in Drosophila, suggesting that key aspects of long-germ segmentation derive from short-germ ancestors.

Segmentation: from Short-Germ to Long-Germ

Image credit: pbio.2002439

09/22/2017

methods and resources

How Bacteria Colonize Plants

Genome-wide mutagenesis of the bacterium Pseudomonas simiae identifies over 100 genes that significantly impact its ability to colonize roots of the plant Arabidopsis thaliana.

How Bacteria Colonize Plants

Image credit: pbio.2002860

09/22/2017

research article

Complex Regulation of Stomatal Closure

Structural, logic-based, and experimental analysis of a plant signal transduction network regulating stomatal closure predicts a novel feedback mechanism involving cytosolic calcium ions.

Complex Regulation of Stomatal Closure

Image credit: James Kremer

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