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Relatedness, Conflict, and the Evolution of Eusociality

March 23, 2015

Relatedness, Conflict, and the Evolution of Eusociality

Xiaoyun Liao, Stephen Rong and David Queller show that the evolution of sterile castes requires genetic relatedness but also involves conflicts between kin; these results contradict recent claims but agree with inclusive fitness theory.

Image credit: Flickr user Todd Huffman

03/20/2015

community page

Why Buy When You Can 3-D Print Your Own Lab Equipment?

Tom Baden, Thomas Euler and colleagues explore free-and-open online designs for self-built, sophisticated lab equipment that provide access to teaching and research tools for an increasingly broad user base worldwide.

Image credit: 10.1371/journal.pbio.1002086.g001

Why Buy When You Can 3-D Print Your Own Lab Equipment?

Recently Published Articles

Current Issue

Current Issue March 2015

03/25/2015

research article

Scribble Regulates CNS Myelination

Research from Andrew Jarjour, Charles ffrench-Constant and co-authors shows that the polarity protein Scribble regulates the formation and properties of myelin sheaths in the central nervous system, both during development and after demyelinating injury.

Image credit: 10.1371/journal.pbio.1002107.g002

Scribble Regulates CNS Myelination

03/26/2015

research article

Voltage-Gated Calcium Channel Regulates Lysosomal Fusion

Xuejun Tian, Upasana Gala, Chao Tong and colleagues discover that a voltage-gated calcium channel required for neurotransmitter release also regulates the fusion of neuronal lysosomes with endosomes and autophagosomes, thereby helping to maintain cellular homeostasis.

Image credit: 10.1371/journal.pbio.1002103

Voltage-Gated Calcium Channel Regulates Lysosomal Fusion

03/25/2015

education

A Biotic Game Design Project

Nate Cira, Alice Chung, Ingmar Riedel-Kruse and co-authors describe a "biotic game design" project to motivate student learning at the interface of life sciences and device engineering.

A Biotic Game Design Project

Image credit: 10.1371/journal.pbio.1002110

03/17/2015

research article and synopsis

Viral Transmission: Stochasticity Drives Adaptation

Shuhei Miyashita, Masayuki Ishikawa and colleagues show how stochastic processes occurring within individual infected cells form a sophisticated adaptation system that optimizes viruses for further infection. Read more in the Synopsis.

Viral Transmission: Stochasticity Drives Adaptation

Image credit: 10.1371/journal.pbio.1002094.g001

03/18/2015

research article

Cell Cycle–Dependent Differentiation in the Pancreas

Yung Hae Kim, Anne Grapin-Botton and co-authors show that during the development of the pancreas, the asymmetric or symmetric differentiation of progenitor cells into endocrine cells results from stochastic priming of mitotic progenitors at different stages of the cell cycle.

Cell Cycle–Dependent Differentiation in the Pancreas

Image credit: 10.1371/journal.pbio.1002111 S1 Fig.

03/13/2015

perspective

Usage and Abusage of the P-Value

Publication bias resulting from "p-hacking" is pervasive throughout the life sciences, but its effects appear to be weak.

Usage and Abusage of the P-Value

03/11/2015

research article

Time-Window Separation Helps Find a Mate

How the conflict between sensory adaptation and sound localization is resolved in the grasshopper auditory system.

Time-Window Separation Helps Find a Mate

Image credit: Flickr user Kumon