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Toxicity versus Virulence in Staphylococcus Infection

September 2, 2015

Toxicity versus Virulence in Staphylococcus Infection

This study from Maisem Laabei, Daniel Wilson, Mario Recker, Ruth Massey and colleagues shows that, contrary to expectation, toxin secretion inversely correlates with disease severity for the major human pathogen Staphylococcus aureus. Read the Synopsis

Image credit: NIAID

09/03/2015

Research Article and primer

Calcium, Actin Nucleation and Neurite Branching

A study by Wenya Hou, Maryam Izadi, Sabine Nemitz, Britta Qualmann and colleagues provides evidence that the calcium sensor calmodulin directly regulates the actin filament-promoting factor Cobl to help shape the complex architecture of neurons underlying neuronal network formation. Read the Primer by George Leondaritis and Britta Eickholt.

Image credit: Natja Haag

Calcium, Actin Nucleation and Neurite Branching

Recently Published Articles

Current Issue

Current Issue August 2015

09/04/2015

Community Page

Centre of the Cell: Science Comes to Life

This Community Page from Frances Balkwill and Katie Chambers describes "Centre of the Cell"—an innovative and successful public engagement project situated inside a research laboratory in London's East End—and its impact on research staff and local audiences.

Image credit: Nick Wood for Land Design Studio

Centre of the Cell: Science Comes to Life

08/27/2015

Research Article

Proteoglycan, Competition and Growth Control

Ana Ferreira and Marco Milán show that the loss of tumor suppressor genes induces a non-autonomous reduction of growth and proliferation rates in adjacent cell populations via competition for available growth factors; the proteoglycan Dally helps mediate this effect.

Image credit: 10.1371/journal.pbio.1002239

Proteoglycan, Competition and Growth Control

08/27/2015

Perspective

Sharing Research Data and Intellectual Property Law

This Perspective by Michael Carroll addresses questions and concerns that biologists often have about intellectual property rights in research data and how these interact with the deposition or sharing of data.

Sharing Research Data and Intellectual Property Law

Image credit: Flickr user Horia Varlan

08/25/2015

Primer

Leaky Vaccination Can Select for Higher Virulence

This Primer from Mike Boots explains how new evidence from studies of Marek’s disease supports evolutionary theory, suggesting that vaccination can select for increased parasite virulence. Read the Research Article

Leaky Vaccination Can Select for Higher Virulence

Image credit: Flickr user Garrett Heath

08/21/2015

Perspective

The Question of Data Integrity in Article-Level Metrics

Article-level metric (ALM) data need to be secure and reliable if they are to be trusted and used by all. This Perspective by Gregg Gordon, Jennifer Lin, Richard Cave and Ralph Dandrea explores the different approaches taken by two organizations to establish ALM data integrity.

The Question of Data Integrity in Article-Level Metrics

Image credit: Flickr user Duncan Hull