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Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

August 24, 2016

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

Thomas Mandel Clausen, Ali Salanti, and colleagues

Image credit: Ayres Pereira M, et al. (2016)

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Current Issue July 2016

08/25/2016

Research Matters

Discovering Protein Receptors for Signaling Nucleotides

In this Research Matters article, Vincent T. Lee discusses his basic research journey. Throughout his career he has studied signal transduction systems used by bacteria to respond to environmental changes. He has found binding proteins in the bacterial cell, and discovered a procedure, Differential Radial Capillary Action of Ligand Assay, to screen thousands of proteins encoded on the bacterial genome.

Image credit: Lee VT (2016)

Discovering Protein Receptors for Signaling Nucleotides