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UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

May 17, 2017

UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

Shin-Ru Shih et al. 

Image credit: Huang P-N, et al. (2017)

PLOS Science Wednesday Cystic Fibrosis AMA

PLOS Pathogens authors Professor Wu and Dr. Scoffield answer questions about their research 

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05/18/2017

Featured research

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

N. Luisa Hiller and colleagues focus on Streptococcus pneumoniae (pneumococcus) and contribute to the knowledge of peptide-communication signals in pneumococcus. Hiller et. al determine that a regulator-peptide signal transduction system, TprA2/PhrA2, was acquired by a PMEN1 ancestor and is encoded by the vast majority of strains in this lineage. 

Image credit: Kadam A, et al. (2017)

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

Recently Published Articles

Current Issue

Current Issue April 2017

05/18/2017

pearls

Targeting pathogen sterols: Defence and counterdefence?

Kemal Kazan and Donald M. Gardiner discuss sterols, a class of lipids found in the cellular membranes of all eukaryotes. Kazan and Gardiner recognize sterol as a target of antifungal chemical compounds and of innate plant defenses. They are interested in the pathogenesis-related protein 1 (PR1) and its newly discovered roles in sterol binding and also look at how counterdefense strategies employed by pathogens neutralize host defenses targeting sterols.

Image credit: Kazan K, et al. (2017)

Targeting pathogen sterols: Defence and counterdefence?

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