Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy
Over the past decade, multiple strategies have been investigated for HIV Cure, such as those inspired by the cure of the Berlin Patient. The goal of Kiem and colleagues is to apply a safer version of this curative approach to more patients, using gene editing to create a similar CCR5 mutation in a patient’s own cells.
Image credit: Peterson CW, et al. (2018)