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GDSL lipases modulate immunity through lipid homeostasis in rice

November 13, 2017

GDSL lipases modulate immunity through lipid homeostasis in rice

Zuhua He and colleagues 

Image credit: Gao M, et al. (2017)

Recently Published Articles

Current Issue

Current Issue October 2017

11/16/2017

Pearls

Poxviruses: Slipping and sliding through transcription and translation

Derek Walsh looks at poxviruses and translational control, and reveals how the study of poxviruses was fundamental to the discovery of the cap and polyA tail that we now know to be present on most eukaryotic mRNAs. Walsh also describes how these viruses have become invaluable tools in oncolytic gene therapy and as vaccine vectors in modern medicine. 

Image credit: Walsh D (2017)

Poxviruses: Slipping and sliding through transcription and translation

11/16/2017

Pearls

Irruptive mammal host populations shape tularemia epidemiology

Juan J. Luque-Larena, François Mougeot, Beatriz Arroyo and colleagues look at tularemia epidemiology and focus on fluctuating mammal populations, irrigation as an amplification agent for tularemia, aquatic and terrestrial agents of tularemia that coexist in nature, host population dynamics, and how tularemia surveillance must target unstable mammalian host populations.

Image credit: Luque-Larena JJ, et al. (2017)

Irruptive mammal host populations shape tularemia epidemiology

11/10/2017

research article

MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner

Jiang and colleagues demonstrate that MAVS activates TBK1/IKKε through TRAFs in both NEMO-dependent and independent manner. Importantly, a minimal amount of IFNs was produced independent of NF-κB activation during virus infection and that individual TRAFs differently mediated TBK1/IKKε activation, thus fine-tuned antiviral immunity under physiological conditions.

MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner

Image credit: Fang R, et al. (2017)

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