About the Authors

Brian B Tuch

Contributed equally to this work with: Brian B Tuch, David J Galgoczy

Affiliations Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America , Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

David J Galgoczy

Contributed equally to this work with: Brian B Tuch, David J Galgoczy

Affiliations Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America , Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

Aaron D Hernday

Affiliations Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America , Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

Hao Li

To whom correspondence should be addressed. E-mail: haoli@genome.ucsf.edu (HL); ajohnson@cgl.ucsf.edu (ADJ)

Affiliation Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

Alexander D Johnson

To whom correspondence should be addressed. E-mail: haoli@genome.ucsf.edu (HL); ajohnson@cgl.ucsf.edu (ADJ)

Affiliations Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America , Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DJG did the experimental work, with contributions from BBT and ADH. BBT performed computational analyses with guidance from HL. BBT wrote the manuscript with editorial support from ADJ and HL and comments from the other authors. HL and ADJ oversaw the work.