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Viral persistence and latency  
PLOS Pathogens  
Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition

Jiayi Wang, Nadine Brückner, Simon Weissmann, Thomas Günther, Shuyong Zhu, Carolin Vogt, Guorong Sun, Rongrong Guo, Renzo Bruno, Birgit Ritter, Lars Steinbrück, Benedikt B. Kaufer, Daniel P. Depledge, Adam Grundhoff, Abel Viejo-Borbolla

Research Article | published 10 Feb 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012367

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Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency

Shirley Man, Jade Jansen, Stefanie Kroeze, Teunis B. H. Geijtenbeek, Neeltje A. Kootstra

Research Article | published 10 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012822

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Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice

Nicole L. Diggins, Andrew H. Pham, Jennifer Mitchell, Christopher J. Parkins, Luke Slind, Rebekah Turner, Byeong-Jae Lee, Andrew D. Yurochko, Patrizia Caposio, Jay A. Nelson, Meaghan H. Hancock

Research Article | published 11 Dec 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012285

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Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells

Stefan D. Klimaj, Autumn LaPointe, Kimberly Martinez, Eduardo Hernandez Acosta, Alison M. Kell

Research Article | published 25 Nov 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012728

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Isotretinoin promotes elimination of translation-competent HIV latent reservoirs in CD4T cells

J. Natalie Howard, Callie Levinger, Selase Deletsu, Rémi Fromentin, Nicolas Chomont, Alberto Bosque, for the AIDS Clinical Trials Group (ACTG) A5325 Team

Research Article | published 14 Oct 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012601

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The unappreciated role of developing B cells in chronic gammaherpesvirus infections

Yiping Wang, April Feswick, Vasiliki Apostolou, Scott A. Tibbetts

Pearls | published 19 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012445

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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal

William J. Cisneros, Shimaa H. A. Soliman, Miriam Walter, Lacy M. Simons, Daphne Cornish, Simone De Fabritiis, Ariel W. Halle, Eun-Young Kim, Steven M. Wolinsky, Ramon Lorenzo-Redondo, Ali Shilatifard, Judd F. Hultquist

Research Article | published 11 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012083

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The DNA loop release factor WAPL suppresses Epstein-Barr virus latent membrane protein expression to maintain the highly restricted latency I program

Laura A. Murray-Nerger, Davide Maestri, Xiang Liu, Zhixuan Li, Nina R. Auld, Italo Tempera, Mingxiang Teng, Benjamin E. Gewurz

Short Reports | published 06 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012525

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Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse

Kylie Nennig, Satyapramod Murthy, Sara Maloney, Teressa M. Shaw, Mark Sharobim, Eduard Matkovic, Simi Fadiran, Malorie Larsen, Mitchell D. Ramuta, Arthur S. Kim, John R. Teijaro, Joe Grove, Matthew Stremlau, Himanshu Sharma, Sheetal Trivedi, Michael J. Blum, David H. O’Connor, Jennifer L. Hyde, Jack T. Stapleton, Amit Kapoor, Adam L. Bailey

Research Article | published 28 Aug 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012436

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HIV transcription persists in the brain of virally suppressed people with HIV

Janna Jamal Eddine, Thomas A. Angelovich, Jingling Zhou, Sarah J. Byrnes, Carolin Tumpach, Nadia Saraya, Emily Chalmers, Rory A. Shepherd, Abigail Tan, Stephanie Marinis, Paul R. Gorry, Jacob D. Estes, Bruce J. Brew, Sharon R. Lewin, Sushama Telwatte, Michael Roche, Melissa J. Churchill

Research Article | published 08 Aug 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012446

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Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

Ranran Wang, Taylor E. Senay, Tiana T. Luo, Wei Liu, James M. Regan, Nicholas J. H. Salisbury, Denise A. Galloway, Jianxin You

Research Article | published 29 Jul 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012170

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Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors

Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei

Research Article | published 12 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012318

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The anti-apoptotic function of HSV-1 LAT in neuronal cell cultures but not its function during reactivation correlates with expression of two small non-coding RNAs, sncRNA1&2

Jay J. Oh, Ujjaldeep Jaggi, Kati Tormanen, Shaohui Wang, Satoshi Hirose, Homayon Ghiasi

Research Article | published 10 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012307

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A novel ilarvirus protein CP-RT is expressed via stop codon readthrough and suppresses RDR6-dependent RNA silencing

Nina Lukhovitskaya, Katherine Brown, Lei Hua, Adrienne E. Pate, John P. Carr, Andrew E. Firth

Research Article | published 30 May 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012034

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Impact of viral telomeric repeat sequences on herpesvirus vector vaccine integration and persistence

Caroline Denesvre, Yu You, Sylvie Rémy, Tereza Vychodil, Katia Courvoisier, Zoltán Penzes, Luca D. Bertzbach, Ahmed Kheimar, Benedikt B. Kaufer

Research Article | published 28 May 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012261

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