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Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases

Lucas Saposnik, Lorena M. Coria, Laura Bruno, Fracisco Guaimas, Julieta Pandolfi, Melina Pol, Maria Eugenia Urga, Florencia Sabbione, Michael McClelland, Analia Trevani, Karina A. Pasquevich, Juliana Cassataro

Research Article | published 28 Mar 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1013013

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Suppressing Tymovirus replication in plants using a variant of ubiquitin

Anuradha De Silva, Kihun Kim, John Weiland, Jihyun Hwang, Jacky Chung, Higor S. Pereira, Trushar R. Patel, Joan Teyra, Ankoor Patel, Mohammed M. Mira, Mazdak Khajehpour, Melvin Bolton, Claudio Stasolla, Sachdev S. Sidhu, Brian L. Mark

Research Article | published 27 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012899

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Diverse autoinhibitory mechanisms of FIIND-containing proteins: Insight into regulation of NLRP1 and CARD8 inflammasome

Jingfan Zhou, Chengrong Liu, Xin Wang, Zhenshan Liu, Zizhen Ming, Yonggang Wang, Chunxia Wang, Qiming Liang

Research Article | published 24 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012877

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Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection

Kiran Bala Sharma, Chandru Subramani, Khashpatika Ganesh, Anshula Sharma, Brohmomoy Basu, Shivani Balyan, Ghanshyam Sharma, Shouri KA, Arundhati Deb, Mitul Srivastava, Saurabh Chugh, Sapna Sehrawat, Kanchan Bharadwaj, Archana Rout, Pankaj Kumar Sahoo, Suman Saurav, Rajender K. Motiani, Ramandeep Singh, Deepti Jain, Shailendra Asthana, Renu Wadhwa, Sudhanshu Vrati

Research Article | published 30 Dec 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012816

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Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection

Fan Bu, Gang Ye, Kimberly Morsheimer, Alise Mendoza, Hailey Turner-Hubbard, Morgan Herbst, Benjamin Spiller, Brian E. Wadzinski, Brett Eaton, Manu Anantpadma, Ge Yang, Bin Liu, Robert Davey, Fang Li

Research Article | published 23 Dec 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012817

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The 2 faces of plant SUMOylation against viruses

Blanca Sabarit, Eduardo R. Bejarano

Pearls | published 17 Dec 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012701

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SARS-CoV-2 Omicron variations reveal mechanisms controlling cell entry dynamics and antibody neutralization

Enya Qing, Julisa Salgado, Alexandria Wilcox, Tom Gallagher

Research Article | published 02 Dec 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012757

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TMPRSS2 in microbial interactions: Insights from HKU1 and TcsH

Zhengyang Pan, Daoqun Li, Leiliang Zhang

Pearls | published 20 Nov 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012677

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ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization

Lu Zhang, Hsiu-Hsin Cheng, Nadine Krüger, Bojan Hörnich, Luise Graichen, Alexander S. Hahn, Sebastian R. Schulz, Hans-Martin Jäck, Metodi V. Stankov, Georg M. N. Behrens, Marcel A. Müller, Christian Drosten, Onnen Mörer, Martin Sebastian Winkler, ZhaoHui Qian, Stefan Pöhlmann, Markus Hoffmann

Research Article | published 13 Nov 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012653

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Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates

Jan Schlötzer, Alexander Schmalix, Sophie Hügelschäffer, Dominic Rieger, Florian Sauer, Mark D. Tully, Thomas Rudel, Silke Wiesner, Caroline Kisker

Research Article | published 21 Oct 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012630

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Tetraspanin-enriched microdomains play an important role in pathogenesis in the protozoan parasite Entamoeba histolytica

Han Jiang, Herbert J. Santos, Tomoyoshi Nozaki

Research Article | published 03 Oct 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012151

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qsmR encoding an IclR-family transcriptional factor is a core pathogenic determinant of Burkholderia glumae beyond the acyl-homoserine lactone-mediated quorum-sensing system

Tiago De Paula Lelis, Jobelle Bruno, Jonas Padilla, Inderjit Barphagha, John Ontoy, Jong Hyun Ham

Research Article | published 03 Oct 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011862

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TRIM56 restricts Coxsackievirus B infection by mediating the ubiquitination of viral RNA-dependent RNA polymerase 3D

Yao Wang, Yanyan Dong, Tian Luan, Yang Chen, Lexun Lin, Siwei Li, Danxiang Feng, Jianwei Wei, Yanru Fei, Guangtian Wang, Jiahui Pan, Yan Wang, Zhaohua Zhong, Wenran Zhao

Research Article | published 30 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012594

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α-Synuclein strain propagation is independent of cellular prion protein expression in a transgenic synucleinopathy mouse model

Raphaella W. L. So, Genki Amano, Erica Stuart, Aeen Ebrahim Amini, Adriano Aguzzi, Graham L. Collingridge, Joel C. Watts

Research Article | published 12 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012517

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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system

Francesco Costacurta, Andrea Dodaro, David Bante, Helge Schöppe, Ju-Yi Peng, Bernhard Sprenger, Xi He, Seyed Arad Moghadasi, Lisa Maria Egger, Jakob Fleischmann, Matteo Pavan, Davide Bassani, Silvia Menin, Stefanie Rauch, Laura Krismer, Anna Sauerwein, Anne Heberle, Toni Rabensteiner, Joses Ho, Reuben S. Harris, Eduard Stefan, Rainer Schneider, Theresia Dunzendorfer-Matt, Andreas Naschberger, Dai Wang, Teresa Kaserer, Stefano Moro, Dorothee von Laer, Emmanuel Heilmann

Research Article | published 11 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012522

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March 2025
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9101112131415
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March 2025
SuMoTuWeThFrSa
2324252627281
2345678
9101112131415
16171819202122
23242526272829
303112345