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PLOS Pathogens  
Liver stage P. falciparum antigens highly targeted by CD4+ T cells in malaria-exposed Ugandan children

Gonzalo R. Acevedo, Sophie S. Samiee, Mikias Ilala, Justine Levan, Meagan E. Olive, Riana D. Hunter, Mary Prahl, Raja Rajalingam, John Rek, Grant Dorsey, Margaret E. Feeney

Research Article | published 24 Feb 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012943

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A paradoxical population structure of var DBLα types in Africa

Mun Hua Tan, Kathryn E. Tiedje, Qian Feng, Qi Zhan, Mercedes Pascual, Heejung Shim, Yao-ban Chan, Karen P. Day

Research Article | published 04 Feb 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012813

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Atypical memory B cells from natural malaria infection produced broadly neutralizing antibodies against Plasmodium vivax variants

Piyawan Kochayoo, Saya Moriyama, Ryutaro Kotaki, Pongsakorn Thawornpan, Chayapat Malee, Chaniya Leepiyasakulchai, Francis Babila Ntumngia, John H. Adams, Yoshimasa Takahashi, Patchanee Chootong

Research Article | published 23 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012866

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Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy

Xin-zhuan Su, Fangzheng Xu, Rachel V. Stadler, Awet Alem Teklemichael, Jian Wu

Review | published 23 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012853

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Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype

Florence E. McLean, Brian R. Omondi, Nouhoum Diallo, Stanley Otoboh, Carolyne Kifude, Abdirahman I. Abdi, Rivka Lim, Thomas D. Otto, Ashfaq Ghumra, J. Alexandra Rowe

Research Article | published 13 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012434

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The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells

Thomas Ogao Onchuru, Edward Edmond Makhulu, Purity Cassandra Ronnie, Stancy Mandere, Fidel Gabriel Otieno, Joseph Gichuhi, Jeremy Keith Herren

Research Article | published 11 Nov 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012340

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A novel broad-spectrum antibacterial and anti-malarial Anopheles gambiae Cecropin promotes microbial clearance during pupation

Cairé Barreto, Victor Cardoso-Jaime, George Dimopoulos

Research Article | published 23 Oct 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012652

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Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR

Ying-An Chen, Eric Neubauer Vickers, Andres Aranda-Diaz, Maxwell Murphy, Inna Gerlovina, Francois Rerolle, Emily Dantzer, Bouasy Hongvanthong, Hsiao-Han Chang, Andrew A. Lover, Nicholas J. Hathaway, Adam Bennett, Bryan Greenhouse

Research Article | published 23 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012194

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Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory

Dinah S. Nahid, Kevin A. Coffey, Amy K. Bei, Regina Joice Cordy

Review | published 19 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012514

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Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies

Feng Lu, Jiahui Xu, Yaobao Liu, Zhenyu Ren, Junhu Chen, Weijuan Gong, Yi Yin, Yinyue Li, Li Qian, Xinlong He, Xiu Han, Zhijie Lin, Jingyuan Lu, Wenwen Zhang, Jiali Liu, Didier Menard, Eun-Taek Han, Jun Cao

Research Article | published 28 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012334

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Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites

Konstantinos Koussis, Silvia Haase, Chrislaine Withers-Martinez, Helen R. Flynn, Simone Kunzelmann, Evangelos Christodoulou, Fairouz Ibrahim, Mark Skehel, David A. Baker, Michael J. Blackman

Research Article | published 27 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012360

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A new landscape for malaria vaccine development

Alexander J. Laurenson, Matthew B. Laurens

Pearls | published 27 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012309

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Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana

Mathieu Vanhove, Philipp Schwabl, Collette Clementson, Angela M. Early, Margaret Laws, Frank Anthony, Célia Florimond, Luana Mathieu, Kashana James, Cheyenne Knox, Narine Singh, Caroline O. Buckee, Lise Musset, Horace Cox, Reza Niles-Robin, Daniel E. Neafsey

Research Article | published 13 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012013

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Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine

Rui Ma, Nichole D. Salinas, Sachy Orr-Gonzalez, Brandi Richardson, Tarik Ouahes, Holly Torano, Bethany J. Jenkins, Thayne H. Dickey, Jillian Neal, Junhui Duan, Robert D. Morrison, Apostolos G. Gittis, Justin Y. A. Doritchamou, Irfan Zaidi, Lynn E. Lambert, Patrick E. Duffy, Niraj H. Tolia

Research Article | published 04 Mar 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011879

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Role of riboflavin deficiency in malaria pathophysiology

Shweta Sharma, Arathy Ramachandran, Amit Sharma

Pearls | published 01 Mar 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011991

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