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Human genomics  
PLOS Pathogens  
Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions

Karen Campos-León, Jack Ferguson, Thomas Günther, C. David Wood, Steven W. Wingett, Selin Pekel, Christy S. Varghese, Leanne S. Jones, Joanne D. Stockton, Csilla Várnai, Michelle J. West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L. Parish

Research Article | published 27 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012506

Views: 574Citations: 0Saves: 0 • Shares: 1

The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection

Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit K. Singh, Gregory J. Bedwell, Alan N. Engelman, Adarsh Dharan, Edward M. Campbell

Research Article | published 17 Jan 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012354

Views: 604Citations: 0Saves: 0 • Shares: 0

The DNA loop release factor WAPL suppresses Epstein-Barr virus latent membrane protein expression to maintain the highly restricted latency I program

Laura A. Murray-Nerger, Davide Maestri, Xiang Liu, Zhixuan Li, Nina R. Auld, Italo Tempera, Mingxiang Teng, Benjamin E. Gewurz

Short Reports | published 06 Sep 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012525

Views: 1046Citations: 0Saves: 0 • Shares: 0

Genomic and functional determinants of host spectrum in Group B Streptococcus

Chiara Crestani, Taya L. Forde, John Bell, Samantha J. Lycett, Laura M. A. Oliveira, Tatiana C. A. Pinto, Claudia G. Cobo-Ángel, Alejandro Ceballos-Márquez, Nguyen N. Phuoc, Wanna Sirimanapong, Swaine L. Chen, Dorota Jamrozy, Stephen D. Bentley, Michael Fontaine, Ruth N. Zadoks

Research Article | published 12 Aug 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012400

Views: 1840Citations: 3Saves: 22 • Shares: 3

The impact of HTLV-1 expression on the 3D structure and expression of host chromatin

Hiroko Yaguchi, Anat Melamed, Saumya Ramanayake, Helen Kiik, Aviva Witkover, Charles R. M. Bangham

Research Article | published 01 Mar 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011716

Views: 985Citations: 0Saves: 3 • Shares: 3

One species, many faces: The underappreciated importance of strain diversity

Jana Nysten, Dimitrios Sofras, Patrick Van Dijck

Pearls | published 25 Jan 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011931

Views: 1554Citations: 5Saves: 0 • Shares: 0

Brain tropism acquisition: The spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis

Iris Yousaf, William W. Hannon, Ryan C. Donohue, Christian K. Pfaller, Kalpana Yadav, Ryan J. Dikdan, Sanjay Tyagi, Declan C. Schroeder, Wun-Ju Shieh, Paul A. Rota, Alison F. Feder, Roberto Cattaneo

Research Article | published 21 Dec 2023 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011817

Views: 4310Citations: 9Saves: 8 • Shares: 69

Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies

Olivia A. Pilling, João L. Reis-Cunha, Cooper A. Grace, Alexander S. F. Berry, Matthew W. Mitchell, Jane A. Yu, Clara R. Malekshahi, Elise Krespan, Christina K. Go, Cláudia Lombana, Yun S. Song, Camila F. Amorim, Alexsandro S. Lago, Lucas P. Carvalho, Edgar M. Carvalho, Dustin Brisson, Phillip Scott, Daniel C. Jeffares, Daniel P. Beiting

Research Article | published 20 Mar 2023 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011230

Views: 2177Citations: 5Saves: 19 • Shares: 17

Genomic changes in Kaposi Sarcoma-associated Herpesvirus and their clinical correlates

Jan Clement Santiago, Scott V. Adams, Andrea Towlerton, Fred Okuku, Warren Phipps, James I. Mullins

Research Article | published 28 Nov 2022 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1010524

Views: 1703Citations: 5Saves: 7 • Shares: 4

Androgen receptor transactivates KSHV noncoding RNA PAN to promote lytic replication–mediated oncogenesis: A mechanism of sex disparity in KS

Mingzhu Ding, Jinfeng Wu, Rui Sun, Lijun Yan, Lei Bai, Jiajian Shi, Hua Feng, Yuqi Zhang, Ke Lan, Xing Wang

Research Article | published 20 Sep 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1009947

Views: 2018Citations: 3Saves: 12 • Shares: 1

ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection

Joseph M. Cabral, Camille H. Cushman, Catherine N. Sodroski, David M. Knipe

Research Article | published 28 Apr 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1009567

Views: 3101Citations: 18Saves: 25 • Shares: 2

Origin and evolution of the zinc finger antiviral protein

Daniel Gonçalves-Carneiro, Matthew A. Takata, Heley Ong, Amanda Shilton, Paul D. Bieniasz

Research Article | published 26 Apr 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1009545

Views: 5931Citations: 58Saves: 40 • Shares: 28

Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy

John M. Coffin, Michael J. Bale, Daria Wells, Shuang Guo, Brian Luke, Jennifer M. Zerbato, Michele D. Sobolewski, Twan Sia, Wei Shao, Xiaolin Wu, Frank Maldarelli, Mary F. Kearney, John W. Mellors, Stephen H. Hughes

Research Article | published 07 Apr 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1009141

Views: 3574Citations: 46Saves: 46 • Shares: 7

A heterochromatin inducing protein differentially recognizes self versus foreign genomes

Eric M. Burton, Ibukun A. Akinyemi, Tiffany R. Frey, Huanzhou Xu, Xiaofan Li, Lai Jing Su, Jizu Zhi, Michael T. McIntosh, Sumita Bhaduri-McIntosh

Research Article | published 17 Mar 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1009447

Views: 2104Citations: 10Saves: 16 • Shares: 2

Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma

Jan Clement Santiago, Jason D. Goldman, Hong Zhao, Alec P. Pankow, Fred Okuku, Michael W. Schmitt, Lennie H. Chen, C. Alexander Hill, Corey Casper, Warren T. Phipps, James I. Mullins

Research Article | published 19 Jan 2021 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1008594

Views: 2766Citations: 15Saves: 33 • Shares: 1

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