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Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions
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Karen Campos-León, Jack Ferguson, Thomas Günther, C. David Wood, Steven W. Wingett, Selin Pekel, Christy S. Varghese, Leanne S. Jones, Joanne D. Stockton, Csilla Várnai, Michelle J. West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L. Parish
Research Article |
published 27 Jan 2025
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1012506
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The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection
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Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit K. Singh, Gregory J. Bedwell, Alan N. Engelman, Adarsh Dharan, Edward M. Campbell
Research Article |
published 17 Jan 2025
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1012354
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The DNA loop release factor WAPL suppresses Epstein-Barr virus latent membrane protein expression to maintain the highly restricted latency I program
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Laura A. Murray-Nerger, Davide Maestri, Xiang Liu, Zhixuan Li, Nina R. Auld, Italo Tempera, Mingxiang Teng, Benjamin E. Gewurz
Short Reports |
published 06 Sep 2024
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1012525
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Genomic and functional determinants of host spectrum in Group B Streptococcus
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Chiara Crestani, Taya L. Forde, John Bell, Samantha J. Lycett, Laura M. A. Oliveira, Tatiana C. A. Pinto, Claudia G. Cobo-Ángel, Alejandro Ceballos-Márquez, Nguyen N. Phuoc, Wanna Sirimanapong, Swaine L. Chen, Dorota Jamrozy, Stephen D. Bentley, Michael Fontaine, Ruth N. Zadoks
Research Article |
published 12 Aug 2024
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1012400
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The impact of HTLV-1 expression on the 3D structure and expression of host chromatin
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Hiroko Yaguchi, Anat Melamed, Saumya Ramanayake, Helen Kiik, Aviva Witkover, Charles R. M. Bangham
Research Article |
published 01 Mar 2024
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1011716
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One species, many faces: The underappreciated importance of strain diversity
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Jana Nysten, Dimitrios Sofras, Patrick Van Dijck
Pearls |
published 25 Jan 2024
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1011931
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Brain tropism acquisition: The spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis
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Iris Yousaf, William W. Hannon, Ryan C. Donohue, Christian K. Pfaller, Kalpana Yadav, Ryan J. Dikdan, Sanjay Tyagi, Declan C. Schroeder, Wun-Ju Shieh, Paul A. Rota, Alison F. Feder, Roberto Cattaneo
Research Article |
published 21 Dec 2023
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1011817
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Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies
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Olivia A. Pilling, João L. Reis-Cunha, Cooper A. Grace, Alexander S. F. Berry, Matthew W. Mitchell, Jane A. Yu, Clara R. Malekshahi, Elise Krespan, Christina K. Go, Cláudia Lombana, Yun S. Song, Camila F. Amorim, Alexsandro S. Lago, Lucas P. Carvalho, Edgar M. Carvalho, Dustin Brisson, Phillip Scott, Daniel C. Jeffares, Daniel P. Beiting
Research Article |
published 20 Mar 2023
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1011230
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Genomic changes in Kaposi Sarcoma-associated Herpesvirus and their clinical correlates
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Jan Clement Santiago, Scott V. Adams, Andrea Towlerton, Fred Okuku, Warren Phipps, James I. Mullins
Research Article |
published 28 Nov 2022
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1010524
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Androgen receptor transactivates KSHV noncoding RNA PAN to promote lytic replication–mediated oncogenesis: A mechanism of sex disparity in KS
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Mingzhu Ding, Jinfeng Wu, Rui Sun, Lijun Yan, Lei Bai, Jiajian Shi, Hua Feng, Yuqi Zhang, Ke Lan, Xing Wang
Research Article |
published 20 Sep 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1009947
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ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection
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Joseph M. Cabral, Camille H. Cushman, Catherine N. Sodroski, David M. Knipe
Research Article |
published 28 Apr 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1009567
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Origin and evolution of the zinc finger antiviral protein
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Daniel Gonçalves-Carneiro, Matthew A. Takata, Heley Ong, Amanda Shilton, Paul D. Bieniasz
Research Article |
published 26 Apr 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1009545
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Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy
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John M. Coffin, Michael J. Bale, Daria Wells, Shuang Guo, Brian Luke, Jennifer M. Zerbato, Michele D. Sobolewski, Twan Sia, Wei Shao, Xiaolin Wu, Frank Maldarelli, Mary F. Kearney, John W. Mellors, Stephen H. Hughes
Research Article |
published 07 Apr 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1009141
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A heterochromatin inducing protein differentially recognizes self versus foreign genomes
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Eric M. Burton, Ibukun A. Akinyemi, Tiffany R. Frey, Huanzhou Xu, Xiaofan Li, Lai Jing Su, Jizu Zhi, Michael T. McIntosh, Sumita Bhaduri-McIntosh
Research Article |
published 17 Mar 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1009447
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Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma
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Jan Clement Santiago, Jason D. Goldman, Hong Zhao, Alec P. Pankow, Fred Okuku, Michael W. Schmitt, Lennie H. Chen, C. Alexander Hill, Corey Casper, Warren T. Phipps, James I. Mullins
Research Article |
published 19 Jan 2021
PLOS Pathogens
https://doi.org/10.1371/journal.ppat.1008594