Search Results | PLOS Pathogens

The anti-apoptotic function of HSV-1 LAT in neuronal cell cultures but not its function during reactivation correlates with expression of two small non-coding RNAs, sncRNA1&2

Jay J. Oh, Ujjaldeep Jaggi, Kati Tormanen, Shaohui Wang, Satoshi Hirose, Homayon Ghiasi

Research Article | published 10 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012307

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Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes

Hafsa Rana, Naomi R. Truong, Blake Johnson, Heeva Baharlou, Jason J. Herbert, Sasikaran Kandasamy, Robert Goddard, Ralph C. Cohen, Michael Wines, Najla Nasr, Andrew N. Harman, Kirstie M. Bertram, Kerrie J. Sandgren, Anthony L. Cunningham

Research Article | published 10 Jun 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012267

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Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity

Qiongqiong Zhou, Deshi Shi, Yan-Dong Tang, Longfeng Zhang, Boli Hu, Chunfu Zheng, Li Huang, Changjiang Weng

Research Article | published 26 Apr 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012146

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Progression of herpesvirus infection remodels mitochondrial organization and metabolism

Simon Leclerc, Alka Gupta, Visa Ruokolainen, Jian-Hua Chen, Kari Kunnas, Axel A. Ekman, Henri Niskanen, Ilya Belevich, Helena Vihinen, Paula Turkki, Ana J. Perez-Berna, Sergey Kapishnikov, Elina Mäntylä, Maria Harkiolaki, Eric Dufour, Vesa Hytönen, Eva Pereiro, Tony McEnroe, Kenneth Fahy, Minna U. Kaikkonen, Eija Jokitalo, Carolyn A. Larabell, Venera Weinhardt, Salla Mattola, Vesa Aho, Maija Vihinen-Ranta

Research Article | published 15 Apr 2024 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011829

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Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors

Selina Pasquero, Francesca Gugliesi, Matteo Biolatti, Valentina Dell’Oste, Camilla Albano, Greta Bajetto, Gloria Griffante, Linda Trifirò, Bianca Brugo, Stefano Raviola, Davide Lacarbonara, Qiao Yang, Sen Sudeshna, Leonard Barasa, Hafeez Haniff, Paul R. Thompson, Santo Landolfo, Marco De Andrea

Research Article | published 06 Dec 2023 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1011849

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Binding of herpesvirus entry mediator (HVEM) and HSV-1 gD affect reactivation but not latency levels