Search Results | PLOS Pathogens

E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence

Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

Research Article | published 07 Feb 2025 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1012914

Views: 875 • Citations: 0 • Saves: 0 • Shares: 1

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer

Ethan L. Morgan, Molly R. Patterson, Emma L. Ryder, Siu Yi Lee, Christopher W. Wasson, Katherine L. Harper, Yigen Li, Stephen Griffin, G. Eric Blair, Adrian Whitehouse, Andrew Macdonald

Research Article | published 18 Jun 2020 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1008624

Views: 4527 • Citations: 60 • Saves: 55 • Shares: 42

Microbiome factors in HPV-driven carcinogenesis and cancers

Daniel Lin, Ramez Kouzy, Joseph Abi Jaoude, Sonal S. Noticewala, Andrea Y. Delgado Medrano, Ann H. Klopp, Cullen M. Taniguchi, Lauren E. Colbert

Pearls | published 04 Jun 2020 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1008524

Views: 4774 • Citations: 62 • Saves: 91 • Shares: 13

Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers

Theofano Panayiotou, Stella Michael, Apostolos Zaravinos, Ece Demirag, Charis Achilleos, Katerina Strati

Research Article | published 16 Apr 2020 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1008468

Views: 4032 • Citations: 17 • Saves: 40 • Shares: 12

Cervicovaginal microbiome and natural history of HPV in a longitudinal study

Mykhaylo Usyk, Christine P. Zolnik, Philip E. Castle, Carolina Porras, Rolando Herrero, Ana Gradissimo, Paula Gonzalez, Mahboobeh Safaeian, Mark Schiffman, Robert D. Burk, Costa Rica HPV Vaccine Trial (CVT) Group

Research Article | published 26 Mar 2020 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1008376

Views: 19069 • Citations: 198 • Saves: 329 • Shares: 24

Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

Ethan L. Morgan, Andrew Macdonald

Research Article | published 21 Jun 2019 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1007835

Views: 8330 • Citations: 118 • Saves: 93 • Shares: 27

The HPV-18 E7 CKII phospho acceptor site is required for maintaining the transformed phenotype of cervical tumour-derived cells

Om Basukala, Suruchi Mittal, Paola Massimi, Marco Bestagno, Lawrence Banks

Research Article | published 22 May 2019 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1007769

Views: 3808 • Citations: 36 • Saves: 28 • Shares: 6

Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β

Michelle Ainouze, Pauline Rochefort, Peggy Parroche, Guillaume Roblot, Issam Tout, François Briat, Claudia Zannetti, Marie Marotel, Nadege Goutagny, Philip Auron, Alexandra Traverse-Glehen, Aude Lunel-Potencier, Francois Golfier, Murielle Masson, Alexis Robitaille, Massimo Tommasino, Christine Carreira, Thierry Walzer, Thomas Henry, Katia Zanier, Gilles Trave, Uzma Ayesha Hasan

Research Article | published 08 Aug 2018 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1007158

Views: 5188 • Citations: 27 • Saves: 37 • Shares: 2

The curious case of APOBEC3 activation by cancer-associated human papillomaviruses

Nicholas A. Wallace, Karl Münger

Opinion | published 11 Jan 2018 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1006717

Views: 4145 • Citations: 27 • Saves: 54 • Shares: 9

KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21^CIP1 suppression of replication stress

David R. Soto, Christopher Barton, Karl Munger, Margaret E. McLaughlin-Drubin

Research Article | published 02 Oct 2017 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1006661

Views: 4820 • Citations: 37 • Saves: 46 • Shares: 4

Viruses and Cancer: An Accidental Journey

Karl Munger

Research Matters | published 08 Sep 2016 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1005573

Views: 3193 • Citations: 2 • Saves: 9 • Shares: 13

A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor

Mojgan Padash Barmchi, Mary Gilbert, Miranda Thomas, Lawrence Banks, Bing Zhang, Vanessa J. Auld

Research Article | published 18 Aug 2016 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1005789

Views: 4536 • Citations: 14 • Saves: 38 • Shares: 9

Immunizing against Anogenital Cancer: HPV Vaccines

Cloe S. Pogoda, Richard B. S. Roden, Robert L. Garcea

Pearls | published 19 May 2016 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1005587

Views: 4670 • Citations: 29 • Saves: 33 • Shares: 6

HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures

Adam Pickard, Simon S. McDade, Marie McFarland, W. Glenn McCluggage, Cosette M. Wheeler, Dennis J. McCance

Research Article | published 24 Jun 2015 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1004988

Views: 3715 • Citations: 23 • Saves: 40 • Shares: 5

Dependence of Intracellular and Exosomal microRNAs on Viral E6/E7 Oncogene Expression in HPV-positive Tumor Cells

Anja Honegger, Daniela Schilling, Sandra Bastian, Jasmin Sponagel, Vladimir Kuryshev, Holger Sültmann, Martin Scheffner, Karin Hoppe-Seyler, Felix Hoppe-Seyler

Research Article | published 11 Mar 2015 PLOS Pathogens

https://doi.org/10.1371/journal.ppat.1004712

Views: 9377 • Citations: 216 • Saves: 205 • Shares: 4

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