Epstein-Barr Virus Nuclear Antigen 3C Stabilizes Gemin3 to Block p53-mediated Apoptosis

Qiliang Cai; Yi Guo; Bingyi Xiao; Shuvomoy Banerjee; Abhik Saha; Jie Lu; Tina Glisovic; Erle S. Robertson

doi:10.1371/journal.ppat.1002418

Open Access

Peer-reviewed

Research Article

Epstein-Barr Virus Nuclear Antigen 3C Stabilizes Gemin3 to Block p53-mediated Apoptosis

Qiliang Cai ,

Contributed equally to this work with: Qiliang Cai, Yi Guo

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Yi Guo ,

Contributed equally to this work with: Qiliang Cai, Yi Guo

Affiliations Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Key Laboratory of AIDS Immunology, Ministry of Health, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning, People's Republic of China
⨯
Bingyi Xiao,

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Shuvomoy Banerjee,

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Abhik Saha,

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Jie Lu,

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Tina Glisovic,

Affiliation Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Erle S. Robertson

* E-mail: erle@mail.med.upenn.edu

Affiliation Department of Microbiology and the Tumor Virology Program, Abramson Comprehensive Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Epstein-Barr Virus Nuclear Antigen 3C Stabilizes Gemin3 to Block p53-mediated Apoptosis

Qiliang Cai, …
Yi Guo,
Bingyi Xiao,
Shuvomoy Banerjee,
Abhik Saha,
Jie Lu,
Tina Glisovic,
Erle S. Robertson

x

Published: December 8, 2011
https://doi.org/10.1371/journal.ppat.1002418

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Apoptosis
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Immunoprecipitation
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Transfection
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Epstein-Barr virus
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Cell proliferation
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