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Pharmacokinetics  
PLOS One  
Population pharmacokinetic analysis of intravenous voriconazole in cancer patients

Zunaira Akbar, Muhammad Usman, Muhammad Aamir, Zikria Saleem, Muhammad Rehan Khan, Abdulwahab Alamri, Mohammed Salem Alharbi, Gamal Eldin Mohamed Osman

Research Article | published 27 Mar 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0318883

Views: 132Citations: 0Saves: 0 • Shares: 0

Effects of sleeve gastrectomy and Roux-en-Y gastric bypass on the pharmacokinetics of gabapentin and pregabalin: A cohort study

Georgios Schoretsanitis, Hege-Merete Krabseth, Magnus Strømmen, Arne Helland, Olav Spigset

Research Article | published 26 Mar 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0319912

Views: 76Citations: 0Saves: 0 • Shares: 0

Screening potential anti-osteoarthritis compounds using molecular docking based on MAPK and NFκB pathways and validating their anti-osteoarthritis effect

Tian-Wang Zhu, Yu Zheng, Rui-Xin Li

Research Article | published 25 Mar 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0319686

Views: 142Citations: 0Saves: 0 • Shares: 0

Predictors of clozapine concentration and psychiatric symptoms in patients with schizophrenia

Sang-In Park, Seoyoung Kim, Kwanwoo Park, Uijeong Yu, Yunjeong Jang, Bo-Hyung Kim, Ji Hyun Lee, Euitae Kim

Research Article | published 06 Mar 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0319037

Views: 401Citations: 0Saves: 2 • Shares: 0

Pharmacometabolomics in TB meningitis—Understanding the pharmacokinetic, metabolic, and immune factors associated with anti-TB drug concentrations in cerebrospinal fluid

Jeffrey M. Collins, Maia Kipiani, Yutong Jin, Ashish A. Sharma, Jeffrey A. Tomalka, Teona Avaliani, Mariam Gujabidze, Tinatin Bakuradze, Shorena Sabanadze, Zaza Avaliani, Henry M. Blumberg, David Benkeser, Dean P. Jones, Charles Peloquin, Russell R. Kempker

Research Article | published 03 Mar 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0315999

Views: 269Citations: 0Saves: 0 • Shares: 0

Oseltamivir-induced hepatotoxicity: A retrospective analysis of the FDA adverse event reporting system

Lurong Yu, Qiumeng Xiang, Limei Liu

Research Article | published 25 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0314970

Views: 378Citations: 0Saves: 0 • Shares: 2

Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial

Niklas Walther, Robert Schultz-Heienbrok, Heino Staß, Victor M. Corman, Nils C. Gassen, Marcel A. Müller, Christian Drosten, Martin Witzenrath, Hweeling Lee, Maximilian G. Posch

Research Article | published 25 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0303924

Views: 404Citations: 0Saves: 0 • Shares: 0

Exploring cotton plant compounds for novel treatments against brain-eating Naegleria fowleri: An In-silico approach

Aqal Zaman, Sana Noor, Iqra Ahmad, Muhammad Shehroz, Nour Alhajri, Sibtain Ahmed, Umar Nishan, Sheheryar Sheheryar, Riaz Ullah, Abdelaaty A. Shahat, Hanna Dib, Mohibullah Shah

Research Article | published 24 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0319032

Views: 466Citations: 0Saves: 3 • Shares: 1

Metabolic pathways of Alternative Lengthening of Telomeres in pan-carcinoma

Isaac Armendáriz-Castillo, Jennyfer García-Cárdenas, Pamela Espinosa, Katherine Hidalgo-Fernández, Lizbeth Peña-Zúñiga, Ronie Martínez, Juan Moromenacho, Andrés Herrera-Yela, Jonathan Cruz-Varela, Anilú Saucedo-Sariñana, María-Esperanza Cerdán, Andrés López-Cortés, Santiago Guerrero

Research Article | published 21 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0314012

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Integration of pharmacodynamics, network pharmacology and metabolomics to elucidate the effect and mechanism of Jingfang Granule in the treatment of Paraquat induced Pulmonary fibrosis

Rujing Yue, Tianye Yang, Dejun Niu, Zhen Zeng, Xishuang Wang, Lihong Pan, Jingchun Yao

Research Article | published 18 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0318246

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In-silico tool based on Boolean networks and meshless simulations for prediction of reaction and transport mechanisms in the systemic administration of chemotherapeutic drugs

Fabián Mauricio Vélez Salazar, Iván David Patiño

Research Article | published 07 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0315194

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Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study

Jia Zhang, Shalesh Gangwar, Nagmi Bano, Shaban Ahmad, Mohammed S. Alqahtani, Khalid Raza

Research Article | published 06 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0313585

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Visceral obesity augments prescription use: An analysis of the cross-sectional study of NHANES 2011–2018

Maximino Acevedo-Fernández, Renata Ochoa Precoma, Leonardo M. Porchia, Victor M. Posadas, Enrique Torres-Rasgado, M. Elba Gonzalez-Mejia, Esther López-Bayghen

Research Article | published 03 Feb 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0318413

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1-Methylxanthine enhances memory and neurotransmitter levels

Ralf Jäger, Sidney Abou Sawan, Marco Orrú, Grant M. Tinlsey, Martin Purpura, Shawn D. Wells, Kylin Liao, Ashok Godavarthi

Research Article | published 16 Jan 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0313486

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Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice

Giada Lavigna, Anna Grasso, Chiara Pasini, Valentina Grande, Laura Mignogna, Elena Restelli, Antonio Masone, Claudia Fracasso, Jacopo Lucchetti, Marco Gobbi, Roberto Chiesa

Research Article | published 13 Jan 2025 PLOS ONE

https://doi.org/10.1371/journal.pone.0317404

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