Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Gap Junctional Communication in Osteocytes Is Amplified by Low Intensity Vibrations In Vitro

Figure 4

Vibration induced GJIC is controlled by Akt signaling.

One hour after vibration treatment, (A) Cx43 mRNA levels remained unchanged. (B) Cx43 protein levels were also unaffected by vibrations (0.15 gā€“100 Hz) without and with Akt inhibition but (C) vibrations increased Akt phosphorylation (ser 473) 2.4-fold. (D) Inhibition of Akt activation also inhibited the vibration induced increase in calcein transference. ***: p<0.001 against control.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0090840.g004