Alveolar leak develops by a rich-get-richer process in ventilator-induced lung injury
Fig 3
Injured fraction of lung cells (PI+/DAPI+) by ventilation group.
*Significantly less than all groups (p≤0.036). PI: propidium iodide, marker of cell membrane disruption, ZEEP: zero end-expiratory pressure, PEEP3: positive end-expiratory pressure = 3 cmH2O, Short: ventilation time 30 min, Mid: ventilation time 60 min, ≥2xH: ventilation until elastance (H) at least doubled.