Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task
Fig 1
Caspr3-KO mice showed low motor learning during the early phase of the rotarod task.
[A] Latency to fall of WT and Caspr3-KO mice during training on the accelerated rotarod for five consecutive days. The performance of Caspr3-KO mice on the first two training days was significantly worse than that of WT mice. Repeated-measures two-way ANOVA was conducted to examine the main effect of genotype on each day (p values indicated). [B] Learning rate of WT and Caspr3-KO mice during training on the accelerated rotarod. The learning rate of Caspr3-KO mice on the first training day was significantly worse than that of WT mice. *p < 0.05, **p < 0.01 by t-test with Bonferroni correction. †p < 0.05 by Mann-Whitney test with Bonferroni correction (number of comparisons was ten for latency to fall, and five for learning rate). n = 12 mice per genotype. Error bars represent SEM.